5-S-cysteinyldopac in human urine.
DOI:
https://doi.org/10.2340/0001555570373377Abstract
5-S-Cysteinyldopac, a compound hitherto demonstrated only in brain tissue, has been isolated and quantified in urine. The urines from 12 individuals were found to contain 20 +/- 9.1 micrograms 5-S-cysteinyldopac/24 hours. Incubation of 5-S-cysteinyldopamine with MAO-containing tissue did not give any formation of 5-S-cysteinyldopac, indicating that this compound is formed by nucleophilic addition of cysteine directly to dopac. The findings give further evidence for a small but significant non-specific oxidation of endogenous catechol derivatives in vivo, a fact to be considered when using 5-S-cysteinyldopa as a measure of pigment metabolism.Downloads
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Published
1990-09-01
How to Cite
Carstam, R., Brinck, C., Fornstedt, B., Rorsman, H., & Rosengren, E. (1990). 5-S-cysteinyldopac in human urine. Acta Dermato-Venereologica, 70(5), 373–377. https://doi.org/10.2340/0001555570373377
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