In situ identification of mononuclear cells infiltrating cutaneous carcinoma: an immuno-histochemical study

Authors

  • G De Panfilis
  • V Colli
  • G Manfredi
  • I Misk
  • S Rima
  • M Zampetti
  • F. Allegra

DOI:

https://doi.org/10.2340/0001555559219222

Abstract

The present study was undertaken in order to investigate the exact nature of the cells surrounding cutaneous tumours. Formalin-fixed, paraffin-embedded sections were tested with a horse antihuman T lymphocyte serum and with IgG, IgA and IgM rabbit antihuman serum. All the sections were respectively treated with rabbit anti-horse or swine antirabbit peroxidase-labelled serum. The advantages offered by the immunoperoxidase technique are briefly discussed. T cells are in overwhelming proportion in comparison with IgG, IgA and IgM bearing cells. This seems a further demonstration that mononuclear infiltrate surrounding cutaneous carcinoma mainly represents a cell-mediated immune response.

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Published

1979-05-01

How to Cite

De Panfilis, G., Colli, V., Manfredi, G., Misk, I., Rima, S., Zampetti, M., & Allegra, F. (1979). In situ identification of mononuclear cells infiltrating cutaneous carcinoma: an immuno-histochemical study. Acta Dermato-Venereologica, 59(3), 219–222. https://doi.org/10.2340/0001555559219222

Issue

Section

Articles