Large doses of glucocorticoid in the treatment of alopecia areata
DOI:
https://doi.org/10.2340/000155555493496Abstract
Severe extensive alopecia areata (totalis) was treated with prednisolone as a single 2 g dose i.v. (22 patients) or 0.5 g daily for 5 days orally (13 patients). Four of the patients responded well, 12 had a poor response and 19 had no response. There was a relapse in some at about 6 months, which could be arrested by a further single i.v. dose, but the risks of this form of therapy are unclear and it cannot be recommended for general use. The clinical response to a single dose of corticosteroid implies, however, that there may be a 'switch' mechanism in certain auto-immune diseases, with an all-or-none response.Downloads
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Published
1975-11-01
How to Cite
Burton, J., & Shuster, S. (1975). Large doses of glucocorticoid in the treatment of alopecia areata. Acta Dermato-Venereologica, 55(6), 493–496. https://doi.org/10.2340/000155555493496
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