Characteristics of Pruritus in Bullous Pemphigoid and Impact on Quality of Life: A Prospective Cohort Study
DOI:
https://doi.org/10.2340/00015555-3683Keywords:
pruritus, itch, bullous pemphigoid, quality of life, 5-D Itch Scale, ItchyQolAbstract
Pruritus is a common symptom of bullous pemphigoid (BP), but has been poorly studied. The aim of this study was to analyse the characteristics of pruritus in patients with BP and its impact on their quality of life. A multicentre prospective observational study (in 15 French hospitals) was performed. A total of 60 patients were included, with a mean age of 77.4 years. Pruritus occurred daily in 85% of patients, with a mean pruritus intensity of 5.2/10. Tingling sensations were present in 72.4% of patients and burning sensations in 68.9%. Pruritus was exacerbated by stress, fatigue and xerosis. The mean ItchyQol score was 56.2/110 and the mean 5-D Itch Scale score was 16.5/25. The severity of pruritus was not related to age, sex, BP activity score, eosinophilia, or anti-BP230 and anti-BP180 autoantibodies. This study revealed that pruritus in BP is poorly tolerated and is an important cause of impaired quality of life.Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Clémence Briand, Greta Gourier, Florence Poizeau, Lamia Jelti, Marie Bachelerie, Gaëlle Quéreux, Géraldine Jeudy, Marie Acquitter, Saskia Ingen-Housz-Oro, Frédéric Caux, Catherine Prost, Anne-Sophie Darrigade, Diane Heron Mermin, Emmanuel Mahé, Catherine Picart Dahan, Marie-Aleth Richard, Caroline Jade Clerc, Camille Salle de Chou, Julie Plée, Claire Abasq-Thomas, Laurent Misery, Emilie Brenaut
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.