Real-world Experience of Abrocitinib on Difficult-to-treat Hand Eczema in Chinese Patients
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https://doi.org/10.2340/actadv.v104.39822Keywords:
Abrocitinib, Efficacy, Hand eczema, SafetyAbstract
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Agner T, Elsner P. Hand eczema: epidemiology, prognosis and prevention. J Eur Acad Dermatol Venereol 2020; 34: 4-12.
https://doi.org/10.1111/jdv.16061 DOI: https://doi.org/10.1111/jdv.16061
Marron SE, Tomas-Aragones L, Navarro-Lopez J, Gieler U, Kupfer J, Dalgard FJ, et al. The psychosocial burden of hand eczema: data from a European dermatological multicentre study. Contact Dermatitis 2018; 78: 406-412.
https://doi.org/10.1111/cod.12973 DOI: https://doi.org/10.1111/cod.12973
Quaade AS, Alinaghi F, Dietz JB, Erichsen CY, Johansen JD. Chronic hand eczema: a prevalent disease in the general population associated with reduced quality of life and poor overall health measures. Contact Dermatitis 2023; 89: 453-463.
https://doi.org/10.1111/cod.14407 DOI: https://doi.org/10.1111/cod.14407
Cheng J, Facheris P, Ungar B, Guttman-Yassky E. Current emerging and investigational drugs for the treatment of chronic hand eczema. Expert Opin Investig Drugs 2022; 31: 843-853.
https://doi.org/10.1080/13543784.2022.2087059 DOI: https://doi.org/10.1080/13543784.2022.2087059
Worm M, Thyssen JP, Schliemann S, Bauer A, Shi VY, Ehst B, et al. The pan-JAK inhibitor delgocitinib in a cream formulation demonstrates dose response in chronic hand eczema in a 16-week randomized phase IIb trial. Br J Dermatol 2022; 187: 42-51.
https://doi.org/10.1111/bjd.21037 DOI: https://doi.org/10.1111/bjd.21037
Jimenez PA, Sofen HL, Bissonnette R, Lee M, Fowler J, Zammit DJ, et al. Oral spleen tyrosine kinase/Janus kinase inhibitor gusacitinib for the treatment of chronic hand eczema: results of a randomized phase 2 study. J Am Acad Dermatol 2023; 89: 235-242.
https://doi.org/10.1016/j.jaad.2023.04.027 DOI: https://doi.org/10.1016/j.jaad.2023.04.027
Rosenberg FM, Loman L, Schuttelaar MLA. Baricitinib treatment of severe chronic hand eczema: two case reports. Contact Dermatitis 2022; 86: 419-421.
https://doi.org/10.1111/cod.14039 DOI: https://doi.org/10.1111/cod.14039
Zalewski A, Szepietowski JC. Topical and systemic JAK inhibitors in hand eczema: a narrative review. Expert Rev Clin Immunol 2023; 19: 365-373.
https://doi.org/10.1080/1744666X.2023.2174526 DOI: https://doi.org/10.1080/1744666X.2023.2174526
Vazquez ML, Kaila N, Strohbach JW, Trzupek JD, Brown MF, Flanagan ME, et al. Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): a selective JAK1 clinical candidate for the treatment of autoimmune diseases. J Med Chem 2018; 61: 1130-1152.
https://doi.org/10.1021/acs.jmedchem.7b01598 DOI: https://doi.org/10.1021/acs.jmedchem.7b01598
Sitaru S, Preis S, Eberlein B. Successful treatment of atopic hand and foot eczema with oral Janus kinase 1 inhibition. Dermatitis 2023; 34: 560.
https://doi.org/10.1089/derm.2022.0030 DOI: https://doi.org/10.1089/derm.2022.0030
Kamphuis E, Boesjes CM, Loman L, Kamsteeg M, Haeck I, Van Lynden-van Nes AMT, et al. Real-world experience of abrocitinib treatment in patients with atopic dermatitis and hand eczema: up to 28-week results from the BioDay Registry. Acta Derm Venereol 2024; 104: adv19454.
https://doi.org/10.2340/actadv.v104.19454 DOI: https://doi.org/10.2340/actadv.v104.19454
Thyssen JP, Schuttelaar MLA, Alfonso JH, Andersen KE, Angelova-Fischer I, Arents BWM, et al. Guidelines for diagnosis, prevention, and treatment of hand eczema. Contact Dermatitis 2022; 86: 357-378.
https://doi.org/10.1111/cod.14035 DOI: https://doi.org/10.1111/cod.14035
Held E, Skoet R, Johansen JD, Agner T. The hand eczema severity index (HECSI): a scoring system for clinical assessment of hand eczema. A study of inter- and intraobserver reliability. Br J Dermatol 2005; 152: 302-307.
https://doi.org/10.1111/j.1365-2133.2004.06305.x DOI: https://doi.org/10.1111/j.1365-2133.2004.06305.x
Futamura M, Leshem YA, Thomas KS, Nankervis H, Williams HC, Simpson EL. A systematic review of Investigator Global Assessment (IGA) in atopic dermatitis (AD) trials: many options, no standards. J Am Acad Dermatol 2016; 74: 288-294.
https://doi.org/10.1016/j.jaad.2015.09.062 DOI: https://doi.org/10.1016/j.jaad.2015.09.062
Naegeli AN, Flood E, Tucker J, Devlen J, Edson-Heredia E. The Worst Itch Numeric Rating Scale for patients with moderate to severe plaque psoriasis or psoriatic arthritis. Int J Dermatol 2015; 54: 715-722
https://doi.org/10.1111/ijd.12645 DOI: https://doi.org/10.1111/ijd.12645
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Copyright (c) 2024 Yiting Li, Xi Tan, Shu Nie, Xin Tian, Zhouwei Wu
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