Bullous Pemphigoid that Developed During Nemolizumab Treatment for Atopic Dermatitis: Two Case Reports

Authors

DOI:

https://doi.org/10.2340/actadv.v104.40634

Keywords:

nemolizumab, atopic dermatitis, bullous pemphigoid, itch, IL-31

Abstract

Abstract is missing (Short communication)

Downloads

Download data is not yet available.

References

Kabashima K, Matsumura T, Komazaki H, Kawashima M, Nemolizumab JPSG. Trial of nemolizumab and topical agents for atopic dermatitis with pruritus. N Engl J Med 2020; 383: 141-150.

https://doi.org/10.1056/NEJMoa1917006

Watanabe Y, Ishiuji Y, Ogawa-Tominaga M, Katsuta M, Asahina A. Real-world clinical efficacy of nemolizumab in Japanese patients with atopic dermatitis. Itch 2023; 33: 691-692.

https://doi.org/10.1097/itx.0000000000000071

Kabashima K, Matsumura T, Komazaki H, Kawashima M, Nemolizumab JPaSG. Nemolizumab plus topical agents in patients with atopic dermatitis (AD) and moderate-to-severe pruritus provide improvement in pruritus and signs of AD for up to 68 weeks: results from two phase III, long-term studies. Br J Dermatol 2022; 186: 642-651.

https://doi.org/10.1111/bjd.20873

Masuyuki R, Sato E, Imafuku S. A case of bullous pemphigoid following administration of anti-IL-31 receptor A antibody. J Dermatol 2024 Mar 20 [Online ahead of print].

https://doi.org/10.1111/1346-8138.17171

Marazza G, Pham HC, Schärer L, Pedrazzetti PP, Hunziker T, Trüeb RM, et al. Incidence of bullous pemphigoid and pemphigus in Switzerland: a 2-year prospective study. Br J Dermatol 2009; 161: 861-868.

https://doi.org/10.1111/j.1365-2133.2009.09300.x

Tasanen K, Varpuluoma O, Nishie W. Dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid. Front Immunol 2019; 10: 1238.

https://doi.org/10.3389/fimmu.2019.01238

Rüdrich U, Gehring M, Papakonstantinou E, Illerhaus A, Engmann J, Kapp A, et al. Eosinophils are a major source of interleukin-31 in bullous pemphigoid. Acta Derm Venereol 2018; 98: 766-771.

https://doi.org/10.2340/00015555-2951

Fassett MS, Braz JM, Castellanos CA, Salvatierra JJ, Sadeghi M, Yu X, et al. IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis. Sci Immunol 2023; 8: eabi6887.

https://doi.org/10.1126/sciimmunol.abi6887

Kakinuma T, Wakugawa M, Nakamura K, Hino H, Matsushima K, Tamaki K. High level of thymus and activation-regulated chemokine in blister fluid and sera of patients with bullous pemphigoid. Br J Dermatol 2003; 148: 203-210.

https://doi.org/10.1046/j.1365-2133.2003.05066.x

Downloads

Published

2024-09-02

How to Cite

Katsuta, M., Kamide, R., Ishiuji, Y., Nobeyama, Y., & Asahina, A. (2024). Bullous Pemphigoid that Developed During Nemolizumab Treatment for Atopic Dermatitis: Two Case Reports. Acta Dermato-Venereologica, 104, adv40634. https://doi.org/10.2340/actadv.v104.40634

Issue

Section

Short Communication

Categories