Paget’s Disease of the Male Breast: A Diagnostic Challenge

Authors

  • Eléna Prospero Dermatology Department, University Hospital of Caen, Caen, France
  • Marie Jouandet Dermatology Department, University Hospital of Caen, Caen, France
  • Jean-Marc Chevallier Dermatology Department, University Hospital of Caen, Caen, France
  • Anne Dompmartin Dermatology Department, University Hospital of Caen, Caen, France
  • Jean-Matthieu L'Orphelin Dermatology Department, University Hospital of Caen, Caen, France

DOI:

https://doi.org/10.2340/actadv.v105.42233

Keywords:

Paget’s disease, Mammary Paget’s disease, Paget’s disease of the breast, Male breast cancer

Downloads

Download data is not yet available.

References

Caliskan M, Gatti G, Sosnovskikh I, Rotmensz N, Botteri E, Musmeci S, et al. Paget's disease of the breast: the experience of the European institute of oncology and review of the literature. Breast Cancer Res Treat 2008; 112: 513-521.

https://doi.org/10.1007/s10549-007-9880-5 DOI: https://doi.org/10.1007/s10549-007-9880-5

Markarian S, Holmes DR. Mammary Paget's disease: an update. Cancers 2022; 14: 2422.

https://doi.org/10.3390/cancers14102422 DOI: https://doi.org/10.3390/cancers14102422

Filho LLL, Lopes IMRS, Lopes LRS, Enokihara MMSS, Michalany AO, Matsunaga N. Mammary and extramammary Paget's disease. An Bras Dermatol 2015; 90: 225-231.

https://doi.org/10.1590/abd1806-4841.20153189 DOI: https://doi.org/10.1590/abd1806-4841.20153189

Adams SJ, Kanthan R. Paget's disease of the male breast in the 21st century: a systematic review. Breast 2016; 29: 14-23.

https://doi.org/10.1016/j.breast.2016.06.015 DOI: https://doi.org/10.1016/j.breast.2016.06.015

Joshi MG, Lee AKC, Loda M, Camus MG, Pedersen C, Heatley GJ, et al. Male breast carcinoma: an evaluation of prognostic factors contributing to a poorer outcome. Cancer 1996; 77: 490-498. DOI: https://doi.org/10.1002/(SICI)1097-0142(19960201)77:3<490::AID-CNCR10>3.0.CO;2-#

https://doi.org/10.1002/(SICI)1097-0142(19960201)77:3<490::AID-CNCR10>3.0.CO;2-#

Janku F, Yap TA, Meric-Bernstam F. Targeting the PI3K pathway in cancer: are we making headway? Nat Rev Clin Oncol 2018; 15: 273-291.

https://doi.org/10.1038/nrclinonc.2018.28 DOI: https://doi.org/10.1038/nrclinonc.2018.28

Song Y, Guerrero-Juarez CF, Chen Z, Tang Y, Ma X, Lv C, et al. The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget's disease. Cell Res 2020; 30: 854-872.

https://doi.org/10.1038/s41422-020-0334-5 DOI: https://doi.org/10.1038/s41422-020-0334-5

Arafah M, Arain SA, Raddaoui EMS, Tulba A, Alkhawaja FH, Al Shedoukhy A. Molecular subtyping of mammary Paget's disease using immunohistochemistry. Saudi Med J 2019; 40: 440-446.

https://doi.org/10.15537/smj.2019.5.23967 DOI: https://doi.org/10.15537/smj.2019.5.23967

Sek P, Zawrocki A, Biernat W, Piekarski JH. HER2 molecular subtype is a dominant subtype of mammary Paget's cells. An immunohistochemical study. Histopathology 2010; 57: 564-571.

https://doi.org/10.1111/j.1365-2559.2010.03665.x DOI: https://doi.org/10.1111/j.1365-2559.2010.03665.x

Published

2025-01-14

How to Cite

Prospero, E., Jouandet, M., Chevallier, J.-M., Dompmartin, A., & L’Orphelin, J.-M. (2025). Paget’s Disease of the Male Breast: A Diagnostic Challenge. Acta Dermato-Venereologica, 105, adv42233. https://doi.org/10.2340/actadv.v105.42233

Issue

Section

Short Communication

Categories