Skin Rash on Immunotherapy: When Trombicula Mimics a Cutaneous Immune-related Adverse Event

Authors

  • Léa Frigout Department of Dermatology, Caen -­ Normandy University Hospital, Caen, France
  • Taha Tagmouti Department of Dermatology, Caen -­ Normandy University Hospital, Caen, France
  • Pierre Goineau Department of Anatomical Pathology, Caen -­ Normandy University Hospital, Caen, France
  • Anne Dompmartin Department of Dermatology, Caen -­ Normandy University Hospital, Caen, France; Caen University, Caen, France
  • Jean Matthieu L’Orphelin Department of Dermatology, Caen -­ Normandy University Hospital, Caen, France; Caen University, Caen, France https://orcid.org/0000-0002-5680-7888

DOI:

https://doi.org/10.2340/actadv.v105.43467

Keywords:

Trombicula autumnalis, trombiculiasis, dermoscopy, entodermoscopy, immunotherapy, immune checkpoint inhibitors

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References

L’Orphelin JM, Cassecuel J, Kandolf L, Harwood CA, Tookey P, Junejo MH, et al. Cutaneous manifestations induced by check point inhibitors in 120 melanoma patients: the European MelSkinTox Study. J Eur Acad Dermatol Venereol 2023; 37: 1606–1615. DOI: https://doi.org/10.1111/jdv.19112

Alexander L, Chen RJ, Buckley CJ. Chigger bites and trombiculiasis. In: StatPearls. Orlando, FL: StatPearls Publishing; 2024.

Stekolnikov AA, Santibáñez P, Palomar AM, Oteo JA. Neotrombicula inopinata (Acari: Trombiculidae): a possible causative agent of trombiculiasis in Europe. Parasites Vectors 2014; 7: 90. DOI: https://doi.org/10.1186/1756-3305-7-90

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Ramondetta A, Ribero S, Peano A, Quaglino P, Broganelli P. In vivo observation of trombiculosis with fluorescence-advanced videodermatoscopy. Emerg Infect Dis 2020; 26: 1904–1905. DOI: https://doi.org/10.3201/eid2608.200077

Di Meo N, Fadel M, Trevisan G. Pushing the edge of dermoscopy in new directions: entomodermoscopy of Trombicula autumnalis. Acta Dermatovenerol Alp Pannonica Adriat 2017; 26: 45–46. DOI: https://doi.org/10.15570/actaapa.2017.14

Nasca MR, Lacarrubba F, Micali G. Diagnosis of trombiculosis by videodermatoscopy. Emerg Infect Dis 2014; 20: 1059–1060. DOI: https://doi.org/10.3201/eid2006.130767

Jones JG. Chiggers. Am Fam Physician 1987; 36: 149–152. DOI: https://doi.org/10.1109/TIM.1987.6312656

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Published

2025-07-08

How to Cite

Frigout, L., Tagmouti, T., Goineau, P., Dompmartin, A., & L’Orphelin, J. M. (2025). Skin Rash on Immunotherapy: When Trombicula Mimics a Cutaneous Immune-related Adverse Event. Acta Dermato-Venereologica, 105, adv43467. https://doi.org/10.2340/actadv.v105.43467

Issue

Vol. 105 (2025)

Section

Short Communication

Categories

License

Copyright (c) 2025 Léa Frigout, Taha Tagmouti, Pierre Goineau, Anne Dompmartin, Jean Matthieu L’Orphelin

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.

Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

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