Intermittent Low-dose Ritlecitinib in Refractory Paediatric Alopecia Areata: A Case Report with Therapeutic Implications

Authors

  • Yunhan Hu Department of Dermatology, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, Hubei, China; School of Medicine, Wuhan University of Science and Technology, Wuhan, Hubei, China
  • Cuilin Xie Department of Dermatology, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, Hubei, China
  • Mengyao Hu Department of Dermatology, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, Hubei, China
  • Yongjun Chen Department of Dermatology, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, Hubei, China
  • Ting Yang Department of Dermatology, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, Hubei, China

DOI:

https://doi.org/10.2340/actadv.v105.43607

Keywords:

Alopecia Areata, ritlecitinib, pre-school children, Treatment, Safety

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References

Lee HH, Gwillim E, Patel KR, Hua T, Rastogi S, Ibler E, et al. Epidemiology of alopecia areata, ophiasis, totalis, and universalis: a systematic review and meta-analysis. J Am Acad Dermatol 2020; 82: 675–682.

https://doi.org/10.1016/j.jaad.2019.08.032 DOI: https://doi.org/10.1016/j.jaad.2019.08.032

Gonzalez ME, Browning J, Smith S, Plotka A, Zhu JD, Parvatini S, et al. A phase 1, open-label study of the pharmacokinetics of ritlecitinib in children aged 6–12 years with alopecia areata. Pediatr Dermatol 2025, Feb 9. [Online ahead of print]

https://doi.org/10.1111/pde.15895 DOI: https://doi.org/10.1111/pde.15895

Huang J, Jian J, Li M, Ji R, Li J, Shi W. Effectiveness and tolerability of ritlecitinib in children with alopecia areata: a case series. J Am Acad Dermatol 2025; 92: 1395–1397.

https://doi.org/10.1016/j.jaad.2025.01.090 DOI: https://doi.org/10.1016/j.jaad.2025.01.090

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Published

2025-06-16

How to Cite

Hu, Y., Xie, C., Hu, M., Chen, Y., & Yang, T. (2025). Intermittent Low-dose Ritlecitinib in Refractory Paediatric Alopecia Areata: A Case Report with Therapeutic Implications. Acta Dermato-Venereologica, 105, adv43607. https://doi.org/10.2340/actadv.v105.43607

Issue

Vol. 105 (2025)

Section

Research letter

Categories

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Copyright (c) 2025 Yunhan Hu, Cuilin Xie, Mengyao Hu, Yongjun Chen, Ting Yang

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