In Vitro Evidence Demonstrating the Nondepleting Mechanism of Action of Amlitelimab, an OX40 Ligand Monoclonal Antibody

Authors

  • James G. Krueger Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA
  • Brian S. Kim Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
  • Stephan Weidinger Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Kiel, Germany
  • Yoko Kataoka Department of Dermatology, Osaka Habikino Medical Center, Habikino, Japan
  • John T. O'Malley Sanofi, Cambridge, MA, USA
  • Karl Yen Sanofi, Rotkreuz, Switzerland
  • Cassie Van Krinks Formerly Sanofi, Cambridge, UK
  • Jose Vela Sanofi, Cambridge, MA, USA

DOI:

https://doi.org/10.2340/actadv.v105.43608

Keywords:

amlitelimab, atopic dermatitis, OX40L, regulatory T-cells, T cells, inflammation, ADCC, non depletion

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References

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Published

2025-08-18

How to Cite

Krueger, J. G., Kim, B. S., Weidinger, S., Kataoka, Y., O’Malley, J. T., Yen, K., … Vela, J. (2025). In Vitro Evidence Demonstrating the Nondepleting Mechanism of Action of Amlitelimab, an OX40 Ligand Monoclonal Antibody. Acta Dermato-Venereologica, 105, adv43608. https://doi.org/10.2340/actadv.v105.43608