Baricitinib 2 mg/day as a Cost-conscious Entry Point to Systemic Therapy in Moderate-to-severe Atopic Dermatitis: Real-world Data from a Japanese Clinic

Authors

DOI:

https://doi.org/10.2340/actadv.v105.43616

Keywords:

Atopic Dermatitis, Baricitinib, JAK inhibitor, pruritus, real world data, low dose

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References

Simpson EL, Bieber T, Eckert L, Wu R, Ardeleanu M, Graham NMH, et al. Patient burden of moderate to severe atopic dermatitis (AD): insights from a phase 2b clinical trial of dupilumab in adults. J Am Acad Dermatol 2016; 74: 491–498. DOI: https://doi.org/10.1016/j.jaad.2015.10.043

Simpson E, Armstrong A, Boguniewicz M, Fuxench ZCC, Feely M, Pierce E, et al. Baricitinib 2 mg for the treatment of atopic dermatitis in North America: long-term efficacy and patient-reported outcomes. Dermatol Ther 2022; 35: e15954. DOI: https://doi.org/10.1111/dth.15954

Silverberg JI, Boguniewicz M, Waibel J, Weisman J, Strowd L, Sun L, et al. Clinical tailoring of baricitinib 2 mg in atopic dermatitis: baseline body surface area and rapid onset of action identifies response at week 16. Dermatol Ther 2022; 12: 137–148. DOI: https://doi.org/10.1007/s13555-021-00640-7

Pourali SP, Nscuti L, Dusetzina SB. Out-of-pocket costs of specialty medications for psoriasis and psoriatic arthritis treatment in the Medicare population. JAMA Dermatol 2021; 157: 1239–1241. DOI: https://doi.org/10.1001/jamadermatol.2021.3616

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Feldman SR, Cox LS, Strowd LC, Gerber RA, Faulkner S, Sierka D, et al. The challenge of managing atopic dermatitis in the United States. Am Health Drug Benefits 2019; 12: 83–93.

Heinz KC, Beaudart C, Willems D, Wiethoff I, Hiligsmann M. Cost-effectiveness of emerging treatments for atopic dermatitis: a systematic review. PharmacoEcon 2023; 41: 1415–1435. DOI: https://doi.org/10.1007/s40273-023-01293-4

Liu B, Song X, Liao S, Luan T, Zhao Z. Comparison of efficacy of baricitinib and dupilumab in the treatment of Chinese moderate-to severe atopic dermatitis: a retrospective study. Int Arch Allergy Immunol 2023; 184: 966–974. DOI: https://doi.org/10.1159/000530394

Published

2025-09-10

How to Cite

Mizuashi, M. (2025). Baricitinib 2 mg/day as a Cost-conscious Entry Point to Systemic Therapy in Moderate-to-severe Atopic Dermatitis: Real-world Data from a Japanese Clinic. Acta Dermato-Venereologica, 105, adv43616. https://doi.org/10.2340/actadv.v105.43616