Touch Avoidance and Emotional Impact in Adults with Chronic Hand Eczema: A Nationwide Cohort Study

Authors

  • Maria O. Christensen Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
  • Lea K. Nymand Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
  • Caroline Olesen Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
  • Silvia Mariel Ferrucci Dermatology Section, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy
  • Marie Louise Schuttelaar Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
  • Jonathan I. Silverberg George Washington University School of Medicine and Health Sciences, Washington, USA
  • Claus Zachariae Department of Dermatology and Allergy, Herlev and Gentofte Hospital, Hellerup, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
  • Simon F. Thomsen Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
  • Jacob P. Thyssen Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
  • Alexander Egeberg Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

DOI:

https://doi.org/10.2340/actadv.v105.43634

Keywords:

disease burden, hand dermatitis, chronic hand eczema, hand eczema, quality of life, touch avoidance

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References

Thyssen JP, Johansen JD, Linneberg A, Menné T. The epidemiology of hand eczema in the general population:

prevalence and main findings. Contact Dermatitis 2010; 62: 75–87. DOI: https://doi.org/10.1111/j.1600-0536.2009.01669.x

Agner T, Andersen KE, Brandao FM, Bruynzeel DP, Bruze M, Frosch P, et al. Hand eczema severity and quality of life: a cross-sectional, multicentre study of hand eczema patients. Contact Dermatitis 2008; 59: 43–47. DOI: https://doi.org/10.1111/j.1600-0536.2008.01362.x

Von Mohr M, Kirsch LP, Fotopoulou A. The soothing function of touch: affective touch reduces feelings of social exclusion. Sci Rep 2017; 7: 13516. DOI: https://doi.org/10.1038/s41598-017-13355-7

Ujitoko Y, Yokosaka T, Ban Y, Ho HN. Tracking changes in touch desire and touch avoidance before and after the COVID-19 outbreak. Front Psychol 2022; 13: 1016909. DOI: https://doi.org/10.3389/fpsyg.2022.1016909

Coenraads PJ, Van Der Walle H, Thestrup-Pedersen K, Ruzicka T, Dreno B, De La Loge C, et al. Construction and validation of a photographic guide for assessing severity of chronic hand dermatitis. Br J Dermatol 2005; 152: 296–301. DOI: https://doi.org/10.1111/j.1365-2133.2004.06270.x

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Weisshaar E, Yüksel YT, Agner T, Larsen LS, Grant L, Arbuckle R, et al. Development and validation of a patient-reported outcome measure of the impact of chronic hand eczema on health-related quality of life: the Hand Eczema Impact Scale (HEIS). Dermatol Ther (Heidelb) 2024; 14: 3047–3070. DOI: https://doi.org/10.1007/s13555-024-01267-0

Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI): a simple practical measure for routine clinical use. Clin Exp Dermatol 1994; 19: 210–216. DOI: https://doi.org/10.1111/j.1365-2230.1994.tb01167.x

Siewertsen M, Näslund-Koch C, Duus Johansen J, Simonsen AB, Nguyen TT, Zachariae C, et al. Psychological burden, anxiety, depression and quality of life in patients with hand eczema: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol 2024; 38: 2049–2050. DOI: https://doi.org/10.1111/jdv.20140

Zalewski A, Krajewski PK, Szepietowski JC. Psychosocial consequences of hand eczema: a prospective cross-sectional study. J Clin Med 2023; 12: 574. DOI: https://doi.org/10.3390/jcm12175741

Published

2025-12-10

How to Cite

Christensen, M. O., Nymand, L. K., Olesen, C., Ferrucci, S. M., Schuttelaar, M. L., Silverberg, J. I., … Egeberg, A. (2025). Touch Avoidance and Emotional Impact in Adults with Chronic Hand Eczema: A Nationwide Cohort Study. Acta Dermato-Venereologica, 105, adv43634. https://doi.org/10.2340/actadv.v105.43634

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