Paraneoplastic Pemphigus Mimicking Pemphigus Herpetiformis – Overlap of Two Diseases

Authors

  • Sakura Maeda Department of Dermatology, Kurume University School of Medicine, Fukuoka, Japan
  • Masahiro Tsutsumi Department of Dermatology, Kurume University School of Medicine, Fukuoka, Japan
  • Kwesi Teye Kurume University Institute of Cutaneous Cell Biology, Fukuoka, Japan
  • Norito Ishii Department of Dermatology, Kurume University School of Medicine, Fukuoka, Japan
  • Hiroshi Koga Department of Dermatology, Kurume University School of Medicine, Fukuoka, Japan

DOI:

https://doi.org/10.2340/actadv.v105.adv-2025-0106

Keywords:

Autoantibodies, desmocollin, malignant neoplasm

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References

Ishii N, Teye K, Fukuda S, Uehara R, Hachiya T, Koga H, et al. Anti-desmocollin autoantibodies in nonclassical pemphigus. Br J Dermatol 2015; 173: 59–68. DOI: https://doi.org/10.1111/bjd.13711

Antiga E, Bech R, Maglie R, Genovese G, Borradori L, Bockle B, et al. S2k guidelines on the management of paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome initiated by the European Academy of Dermatology andVenereology (EADV). J Eur Acad Dermatol Venereol 2023; 37: 1118–1134. DOI: https://doi.org/10.1111/jdv.18931

Kasperkiewicz M, Kowalewski C, Jabłońska S. Pemphigus herpetiformis: from first description until now. J Am Acad Dermatol 2014; 70: 780–787. DOI: https://doi.org/10.1016/j.jaad.2013.11.043

Kakurai M, Takeshita H, Koga H, Ishii N, Moriyama Y. A case of pemphigus herpetiformis strongly associated with gastric cancer. Acta Derm Venereol 2024; 104: adv41319. DOI: https://doi.org/10.2340/actadv.v104.41319

Rubin A, Ashforth G, Chamorro P, Blaszczyk MB, Maghari A, Pappert A. Paraneoplastic pemphigus without mucosal lesions in a patient with ovarian cancer. Int J Dermatol 2022; 61: 611–612. DOI: https://doi.org/10.1111/ijd.15667

Prado R, Brice SL, Fukuda S, Hashimoto T, Fujita M. Paraneoplastic pemphigus herpetiformis with IgG antibodies to desmoglein 3 and without mucosal lesions. Arch Dermatol 2011; 147: 67–71. DOI: https://doi.org/10.1001/archdermatol.2010.362

Gallo E, García-Martín P, Fraga J, Teye K, Koga H, Hashimoto T, et al. Paraneoplastic pemphigus with eosinophilic spongiosis and autoantibodies against desmocollins 2 and 3. Clin Exp Dermatol 2014; 39: 323–326. DOI: https://doi.org/10.1111/ced.12296

Published

2025-12-22

How to Cite

Maeda, S., Tsutsumi, M., Teye, K., Ishii, N., & Koga, H. (2025). Paraneoplastic Pemphigus Mimicking Pemphigus Herpetiformis – Overlap of Two Diseases. Acta Dermato-Venereologica, 105, adv–2025. https://doi.org/10.2340/actadv.v105.adv-2025-0106

Issue

Section

Research letter