Multiple Oral White Papules in a 3-year-old Girl: A Quiz

Authors

  • Jeanne Betton Unit of Pediatric Dermatology, Reference Center for Rare Diseases and Vascular Malformations (MAGEC), University Hospital Center of Tours, Tours, France
  • Thibault Kervarrec Department of Pathology, University Hospital Center of Tours, Tours, France
  • Thomas Didier Department of Oral and maxillofacial Surgery, University Hospital Center of Tours, Tours, France
  • Catherine Gaudy-Graffin Department of Bacteriology, Virology and Hospital Hygiene, University Hospital Center of Tours, Tours, France; University of Tours, University of Nantes, INSERM 1246-SPHERE, Tours, France
  • Mahtab Samimi Department of Adult Dermatology, University Hospital Center of Tours, Tours, France
  • Sophie Leducq Unit of Pediatric Dermatology, Reference Center for Rare Diseases and Vascular Malformations (MAGEC), University Hospital Center of Tours, Tours, France; University of Tours, University of Nantes, INSERM 1246-SPHERE, Tours, France; Department of Adult Dermatology, University Hospital Center of Tours, Tours, France

DOI:

https://doi.org/10.2340/actadv.v106.adv-2025-0086

Keywords:

Heck’s disease, mouth mucosa, children

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References

Sethi S, Ali A, Ju X, Antonsson A, Logan R, Jamieson L. An update on Heck’s disease-a systematic review. J Public Health (Oxf) 2022; 44: 269–285. DOI: https://doi.org/10.1093/pubmed/fdaa256

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Nallanchakrava S, Sreebala N, Basavaraj Sindgi F. Laser excision of focal epithelial hyperplasia (Heck’s Disease): a rare case report. Int J Clin Pediatr Dent 2018; 11: 526–528. DOI: https://doi.org/10.5005/jp-journals-10005-1569

Yasar S, Mansur AT, Serdar ZA, Goktay F, Aslan C. Treatment of focal epithelial hyperplasia with topical imiquimod: report of three cases. Pediatr Dermatol 2009; 26: 465–468. DOI: https://doi.org/10.1111/j.1525-1470.2009.00954.x

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Henke R, Guérin‐Reverchon I, Milde‐Langosch K, Koppang HS, Löning T. In situ detection of human papillomavirus types 13 and 32 in focal epithelial hyperplasia of the oral mucosa. J Oral Pathology Medicine 1989; 18: 419–421. DOI: https://doi.org/10.1111/j.1600-0714.1989.tb01575.x

Jiménez Aguilar SM, Rodríguez DL, Muñoz Estrada VF, Cázarez Salazar SG, Velarde Félix JS, Méndez Martínez RS. Great diversity of oncogenic human papillomaviruses is revealed in an outbreak of multifocal epithelial hyperplasia. J Am Acad Dermatol 2023; 88: 1115–1117. DOI: https://doi.org/10.1016/j.jaad.2019.12.041

García-Corona C, Vega-Memije E, Mosqueda-Taylor A, Yamamoto-Furusho JK, Rodríguez-Carreón AA, Ruiz-Morales JA, et al. Association of HLA-DR4 (DRB1*0404) with human papillomavirus infection in patients with focal epithelial hyperplasia. Arch Dermatol 2004; 140: 1227–1231. DOI: https://doi.org/10.1001/archderm.140.10.1227

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Published

2026-02-09

How to Cite

Betton, J., Kervarrec, T., Didier, T., Gaudy-Graffin, C., Samimi, M., & Leducq, S. (2026). Multiple Oral White Papules in a 3-year-old Girl: A Quiz. Acta Dermato-Venereologica, 106, adv–2025. https://doi.org/10.2340/actadv.v106.adv-2025-0086

Issue

Vol. 106 (2026)

Section

Quiz

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