Low Subcutaneous Adipose Tissue is Associated with Poor Prognosis for Aged Patients with Cutaneous Angiosarcoma: A Retrospective Cohort Study

Authors

  • Akira Miyazaki Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Mariko Ogawa-Momohara Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Tomoki Taki Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Shoichiro Mori Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Masashi Akiyama Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan

DOI:

https://doi.org/10.2340/actadv.v106.adv-2025-0058

Keywords:

Adipose Tissue, Computed Tomography, Elderly, Cutaneous angiosarcoma, prognosis

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References

Tu H, McQuade JL, Davies MA, Huang M, Xie K, Ye Y, et al. Body mass index and survival after cancer diagnosis: a pan-cancer cohort study of 114 430 patients with cancer. Innovation 2022; 3: 100344. DOI: https://doi.org/10.1016/j.xinn.2022.100344

Orphanidou C, McCargar L, Birmingham CL, Mathieson J, Goldner E. Accuracy of subcutaneous fat measurement: comparison of skinfold calipers, ultrasound, and computed tomography. J Am Diet Assoc 1994; 94: 855–858. DOI: https://doi.org/10.1016/0002-8223(94)92363-9

Ebadi M, Martin L, Ghosh S, Field CJ, Lehner R, Baracos VE, et al. Subcutaneous adiposity is an independent predictor of mortality in cancer patients. Br J Cancer 2017; 117: 148–155. DOI: https://doi.org/10.1038/bjc.2017.149

Mengoni M, Braun AD, Hinnerichs MS, Tüting T, Surov A. Subcutaneous fat abundance and density are associated with an enhanced response to immunotherapy in metastatic melanoma: a retrospective cohort study. Acad Radiol 2023; 30 Suppl 1: S257–S267. DOI: https://doi.org/10.1016/j.acra.2023.05.007

Tamiya H, Imura Y, Wakamatsu T, Takenaka S. Comorbidity, body mass index, and performance status as prognostic factors in older patients with soft-tissue sarcoma. J Geriatr Oncol 2022; 13: 673–681. DOI: https://doi.org/10.1016/j.jgo.2022.02.011

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Lihn AS, Bruun JM, He G, Pedersen SB, Jensen PF, Richelsen B. Lower expression of adiponectin mRNA in visceral adipose tissue in lean and obese subjects. Mol Cell Endocrinol 2004; 219: 9–15. DOI: https://doi.org/10.1016/j.mce.2004.03.002

Nakamura Y, Sekikawa A, Kadowaki T, Kadota A, Kadowaki S, Maegawa H, et al. Visceral and subcutaneous adiposity and adiponectin in middle-aged Japanese men: the ERA JUMP study. Obesity 2009; 17: 1269–1273. DOI: https://doi.org/10.1038/oby.2009.3

Published

2026-02-11

How to Cite

Miyazaki, A., Ogawa-Momohara, M., Taki, T., Mori, S., & Akiyama, M. (2026). Low Subcutaneous Adipose Tissue is Associated with Poor Prognosis for Aged Patients with Cutaneous Angiosarcoma: A Retrospective Cohort Study. Acta Dermato-Venereologica, 106, adv–2025. https://doi.org/10.2340/actadv.v106.adv-2025-0058

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