Patients with Positive Blood Cultures in Cellulitis: A Large Single-centre Study

Authors

  • Sonja Aaltonen Faculty of Medicine, University of Oulu, Oulu, Finland
  • Jari Jokelainen Northern Finland Birth Cohorts, Arctic Biobank, Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland https://orcid.org/0000-0003-4629-0560
  • Vilma Kantonen Faculty of Medicine, University of Oulu, Oulu, Finland
  • Juulia Kinnunen Faculty of Medicine, University of Oulu, Oulu, Finland
  • Laura Huilaja Department of Dermatology, University Hospital of Oulu, Oulu, Finland; Medical Research Center, Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland https://orcid.org/0000-0002-7597-4323
  • Suvi-Päivikki Sinikumpu Department of Dermatology, University Hospital of Oulu, Oulu, Finland; Medical Research Center, Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland https://orcid.org/0000-0001-6496-5475

DOI:

https://doi.org/10.2340/actadv.v106.adv-2025-0022

Keywords:

cellulitis, bacteraemia, blood cultures, risk factors

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References

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Celestin R, Brown J, Kihiczak G, Schwartz RA. Erysipelas: a common potentially dangerous infection. Acta Dermatovenerol Alp Pannonica Adriat 2007; 16: 123–127.

Boettler MA, Kaffenberger BH, Chung CG. Cellulitis: a review of current practice guidelines and differentiation from pseudocellulitis. Am J Clin Dermatol 2022; 23: 153–165. DOI: https://doi.org/10.1007/s40257-021-00659-8

Taniguchi T, Tsuha S, Shiiki S, Narita M, Teruya M, Hachiman T, et al. High yield of blood cultures in the etiologic diagnosis of cellulitis, erysipelas, and cutaneous abscess in elderly patients. Open Forum Infect Dis 2022; 9: ofac317. DOI: https://doi.org/10.1093/ofid/ofac317

Paolo WF, Poreda AR, Grant W, Scordino D, Wojcik S. Blood culture results do not affect treatment in complicated cellulitis. J Emerg Med 2013; 45: 163–167. DOI: https://doi.org/10.1016/j.jemermed.2013.01.016

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Ihoinfektiot. Käypä hoito -suositus. Suomalaisen lääkäriseuran Duodecimin ja Suomen ihotautilääkäriyhdistys ry:n asettama työryhmä. Helsinki: Suomalainen lääkäriseura Duodecim; 2023. Available from: www.kaypahoito.fi

Lee CY, Kunin CM, Chang C, Lee SJ, Chen YS, Tsai HC. Development of a prediction model for bacteremia in hospitalized adults with cellulitis to aid in the efficient use of blood cultures: a retrospective cohort study. BMC Infect Dis 2016; 16: 581. DOI: https://doi.org/10.1186/s12879-016-1907-2

Perl B, Gottehrer NP, Raveh D, Schlesinger Y, Rudensky B, Yinnon AM. Cost-effectiveness of blood cultures for adult patients with cellulitis. Clin Infect Dis 1999; 29: 1483–1488. DOI: https://doi.org/10.1086/313525

Collazos J, de la Fuente B, de la Fuente J, García A, Gómez H, Menéndez C, et al. Factors associated with sepsis development in 606 Spanish adult patients with cellulitis. BMC Infect Dis 2020; 20: 211 DOI: https://doi.org/10.1186/s12879-020-4915-1

Halavaara M, Jääskeläinen IH, Hagberg L, Järvinen A. Factors associated with blood culture positivity in patients with complicated skin and skin structure infection-a population-based study. Eur J Clin Microbiol Infect Dis 2019; 38: 1351–1357. DOI: https://doi.org/10.1007/s10096-019-03560-9

Bauer S, Aubert CE, Richli M, Chuard C. Blood cultures in the evaluation of uncomplicated cellulitis. Eur J Intern Med 2016; 36: 50–56. DOI: https://doi.org/10.1016/j.ejim.2016.07.029

Peralta G, Padrón E, Roiz MP, De Benito I, Garrido JC, Talledo F, et al. Risk factors for bacteremia in patients with limb cellulitis. Eur J Clin Microbiol Infect Dis 2006; 25: 619–626. DOI: https://doi.org/10.1007/s10096-006-0186-z

Published

2026-02-25

How to Cite

Aaltonen, S., Jokelainen, J., Kantonen, V., Kinnunen, J., Huilaja, L., & Sinikumpu, S.-P. (2026). Patients with Positive Blood Cultures in Cellulitis: A Large Single-centre Study. Acta Dermato-Venereologica, 106, adv–2025. https://doi.org/10.2340/actadv.v106.adv-2025-0022

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