Clinically Meaningful Improvement in Atopic Dermatitis According to Treatment Type in a Real-World Cohort

Authors

  • Emanuel Chew Bonilla Department of Dermatology, Hospital de Especialidades “Dr. Bernardo Sepúlveda Gutiérrez”, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico https://orcid.org/0009-0006-0564-6187
  • Yazmín Xurami Vega-Del Pilar Department of Dermatology, Hospital de Especialidades “Dr. Bernardo Sepúlveda Gutiérrez”, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico https://orcid.org/0009-0001-3986-1321
  • Eduardo Vilchis Chaparro Center for Educational Research and Faculty Development, Hospital de Especialidades “Dr. Bernardo Sepúlveda Gutiérrez”, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico https://orcid.org/0000-0002-4019-9742
  • Alicia Lemini López Department of Dermatology, Hospital de Especialidades “Dr. Bernardo Sepúlveda Gutiérrez”, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico https://orcid.org/0000-0002-7051-1098

DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0422

Keywords:

atopic dermatitis, minimal clinically important difference, SCORAD, DLQI, biologics, Janus kinase inhibitors

Downloads

Download data is not yet available.

References

Schram ME, Spuls PI, Leeflang MMG, Lindeboom R, Bos JD, Schmitt J. EASI, (objective) SCORAD and POEM for atopic eczema: responsiveness and minimal clinically important difference. Allergy 2012; 67: 99–106. DOI: https://doi.org/10.1111/j.1398-9995.2011.02719.x

Basra MKA, Salek MS, Camilleri L, Sturkey R, Finlay AY. Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data. Dermatology 2015; 230: 27–33. DOI: https://doi.org/10.1159/000365390

Ständer S. Atopic dermatitis. N Engl J Med 2021; 384: 1136–1143. DOI: https://doi.org/10.1056/NEJMra2023911

Fasseeh AN, Elezbawy B, Korra N, Tannira M, Dalle H, Aderian S, et al. Burden of atopic dermatitis in adults and adolescents: a systematic literature review. Dermatol Ther 2022; 12: 2653–2668. DOI: https://doi.org/10.1007/s13555-022-00819-6

Wollenberg A, Christen-Zäch S, Taieb A, Paul C, Thyssen JP, de Bruin-Weller M, et al. ETFAD/EADV Eczema task force 2020 position paper on diagnosis and treatment of atopic dermatitis in adults and children. J Eur Acad Dermatol Venereol 2020; 34: 2717–2744. DOI: https://doi.org/10.1111/jdv.16892

Kim RW, Lam M, Abuabara K, Simpson EL, Drucker AM. Targeted systemic therapies for adults with atopic dermatitis: selecting from biologics and JAK inhibitors. Am J Clin Dermatol 2024; 25: 179–193. DOI: https://doi.org/10.1007/s40257-023-00837-w

Siegels D, Heratizadeh A, Abraham S, Binnmyr J, Brockow K, Irvine AD, et al. Systemic treatments in the management of atopic dermatitis: a systematic review and meta-analysis. Allergy 2021; 76: 1053–1076. DOI: https://doi.org/10.1111/all.14631

Rogner D, Biedermann T, Lauffer F. Treatment of atopic dermatitis with baricitinib: first real-life experience. Acta Derm Venereol 2022; 102: adv00677. DOI: https://doi.org/10.2340/actadv.v102.1088

Published

2026-03-12

How to Cite

Chew Bonilla, E., Vega-Del Pilar, Y. X., Vilchis Chaparro, E., & Lemini López, A. (2026). Clinically Meaningful Improvement in Atopic Dermatitis According to Treatment Type in a Real-World Cohort. Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0422

Issue

Section

Research letter

Categories