Painful Destructive Plaques of the Face and Scalp: A Quiz

Authors

  • Rundong Zhang Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China https://orcid.org/0000-0001-5723-675X
  • Zequn Qiu Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China
  • Hongyin Chen Department of Physical Therapy, Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China
  • Hao Chen Department of Pathology, Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China

DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0718

Keywords:

Pyoderma gangrenosum, neutrophilic dermatosis, pathergy, head and neck

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References

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Reese AM, Gupta AS, Latour E, Loyo M, Kaffenberger B, Creadore A, et al. Clinical characteristics and misdiagnosis of pyoderma gangrenosum of the head and neck: a retrospective study. J Am Acad Dermatol 2022; 87: 1130–1133. DOI: https://doi.org/10.1016/j.jaad.2022.02.008

Kaur M, Anthony MR, Yamakoshi C, Schildmeyer A, Mallela T, Diaz MJ, et al. Clinical characteristics, treatments, and outcomes of pyoderma gangrenosum of the face: a systematic review. Int Wound J 2025; 22: e70334. DOI: https://doi.org/10.1111/iwj.70334

Shavit E, Cecchini M, Limacher JJ, Walsh S, Wentworth A, Davis MDP, et al. Superficial granulomatous pyoderma gangrenosum involving the face: a case series of five patients and a review of the literature. J Cutan Med Surg 2021; 25: 371–376. DOI: https://doi.org/10.1177/1203475420988864

Hoang M, Maymone MBC, Telang GH, Seo SJ, Robinson-Bostom L. Vegetative pyoderma gangrenosum mimicking squamous cell carcinoma: a poorly recognized diagnostic challenge. Am J Dermatopathol 2025; 47: e47–e49. DOI: https://doi.org/10.1097/DAD.0000000000002919

Gupta AS, Ortega-Loayza AG. Ocular pyoderma gangrenosum: a systematic review. J Am Acad Dermatol 2017; 76: 512–518. DOI: https://doi.org/10.1016/j.jaad.2016.08.049

Beck DB, Ferrada MA, Sikora KA, Ombrello AK, Collins JC, Pei W, et al. Somatic mutations in UBA1 and severe adult-onset autoinflammatory disease. N Engl J Med 2020; 383: 2628–2638. DOI: https://doi.org/10.1056/NEJMoa2026834

Tan IJ, Ferrada MA, Ahmad S, Fike A, Quinn KA, Groarke EM, et al. Skin manifestations of VEXAS syndrome and associated genotypes. JAMA Dermatol 2024; 160: 822–829. DOI: https://doi.org/10.1001/jamadermatol.2024.1657

Croitoru DO, Huang RS, McMullen EP, Maazi M, Piguet V. Investigating historic cases of pyoderma gangrenosum in myelodysplastic syndrome and chronic myelomonocytic leukemia for possible VEXAS syndrome: a systematic review. J Am Acad Dermatol 2024; 91: 712–714. DOI: https://doi.org/10.1016/j.jaad.2024.05.086

Montagnon CM, Fracica EA, Patel AA, Camilleri MJ, Murad MH, Dingli D, et al. Pyoderma gangrenosum in hematologic malignancies: a systematic review. J Am Acad Dermatol 2020; 82: 1346–1359. DOI: https://doi.org/10.1016/j.jaad.2019.09.032

Published

2026-06-15

How to Cite

Zhang, R., Qiu, Z., Chen, H., & Chen, H. (2026). Painful Destructive Plaques of the Face and Scalp: A Quiz. Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0718