An 8-year-old Girl with Multiple Whitish Dots on the Hair Shaft: A Quiz

Authors

  • Jiamin Xu Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China
  • Yanjun Tang Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China
  • Xiqing Li Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China
  • Fengjie Liu Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China https://orcid.org/0000-0002-5631-7336

DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0421

Keywords:

Hair disorder, Pili annulati, Dermoscopy, Zebra stripe sign, Air-filled cavities, Electron microscopy

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References

Giehl KA, Ferguson DJP, Dawber RPR, Pittelkow MR, Foehles J, de Berker DAR. Update on detection, morphology and fragility in pili annulati in three kindreds. J Eur Acad Dermatol Venereol 2004; 18: 654–658. DOI: https://doi.org/10.1111/j.1468-3083.2004.01036.x

Nam CH, Park M, Choi MS, Hong SP, Kim MH, Park BC. Pili annulati with multiple fragile hairs. Ann Dermatol 2017; 29: 254–256. DOI: https://doi.org/10.5021/ad.2017.29.2.254

Giehl KA, Schmuth M, Tosti A, De Berker DA, Crispin A, Wolff H, et al. Concomitant manifestation of pili annulati and alopecia areata: Coincidental rather than true association. Acta Derm Venereol 2011; 91: 459–462. DOI: https://doi.org/10.2340/00015555-1088

Castelli E, Fiorella S, Caputo V. Pili annulati coincident with alopecia areata, autoimmune thyroid disease, and primary IgA deficiency: Case report and considerations on the literature. Case Rep Dermatol 2012; 4: 250–255. DOI: https://doi.org/10.1159/000345469

Chen S, Yang X, Lu Z. Pili annulati under the electron microscope: A case report and literature review. Clin Exp Dermatol 2025; 50: 424–425. DOI: https://doi.org/10.1093/ced/llae365

Lee SS, Lee YS, Giam YC. Pseudopili annulati in a dark-haired individual: A light and electron microscopic study. Pediatr Dermatol 2001; 18: 27–30. DOI: https://doi.org/10.1046/j.1525-1470.2001.018001027.x

Ahmed A, Almohanna H, Griggs J, Tosti A. Genetic hair disorders: A review. Dermatol Ther (Heidelb) 2019; 9: 421–448. DOI: https://doi.org/10.1007/s13555-019-0313-2

Giehl KA, Rogers MA, Radivojkov M, Tosti A, de Berker DAR, Weinlich G, et al. Pili annulati: Refinement of the locus on chromosome 12q24.33 to a 2.9-Mb interval and candidate gene analysis. Br J Dermatol 2009; 160: 527–533. DOI: https://doi.org/10.1111/j.1365-2133.2008.08948.x

Giehl KA, Ferguson DJP, Dean D, Chuang YH, Allen J, Berker DARD, et al. Alterations in the basement membrane zone in pili annulati hair follicles as demonstrated by electron microscopy and immunohistochemistry. Br J Dermatol 2004; 150: 722–727. DOI: https://doi.org/10.1111/j.0007-0963.2004.05837.x

Singh G, Miteva M. Prognosis and management of congenital hair shaft disorders without fragility-part II. Pediatr Dermatol 2016; 33: 481–487. DOI: https://doi.org/10.1111/pde.12902

Published

2026-07-01

How to Cite

Xu, J., Tang, Y., Li, X., & Liu, F. (2026). An 8-year-old Girl with Multiple Whitish Dots on the Hair Shaft: A Quiz. Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0421