Real-world Outcomes of Adalimumab in Hidradenitis Suppurativa: A 10-year Retrospective Longitudinal Study

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DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0636

Keywords:

Adalimumab, Hidradenitis suppurativa, Treatment outcomes

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References

Sabat R, Alavi A, Wolk K, Wortsman X, McGrath B, Garg A, et al. Hidradenitis suppurativa. Lancet 2025; 405: 420–438. DOI: https://doi.org/10.1016/S0140-6736(24)02475-9

Kimball AB, Okun MM, Williams DA, Gottlieb AB, Papp KA, Zouboulis CC, et al. Two phase 3 trials of adalimumab for hidradenitis suppurativa. N Engl J Med 2016; 375: 422–434. DOI: https://doi.org/10.1056/NEJMoa1504370

Zouboulis CC, Bechara FG, Benhadou F, Bettoli V, Bukvić Mokos Z, Del Marmol V, et al. European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: treatment. J Eur Acad Dermatol Venereol 2025; 39: 899–941. DOI: https://doi.org/10.1111/jdv.20472

Kimball AB, Jemec GBE, Yang M, Kageleiry A, Signorovitch JE, Okun MM, et al. Assessing the validity, responsiveness and meaningfulness of the Hidradenitis Suppurativa Clinical Response (HiSCR) as the clinical endpoint for hidradenitis suppurativa treatment. Br J Dermatol 2014; 171: 1434–1442. DOI: https://doi.org/10.1111/bjd.13270

Elzawawi KE, Elmakaty I, Habibullah M, Ahmed MB, Al Lahham S, Al Harami S, et al. Hidradenitis suppurativa and its association with obesity, smoking, and diabetes mellitus: a systematic review and meta-analysis. Int Wound J 2024; 21: e70035. DOI: https://doi.org/10.1111/iwj.70035

Kokolakis G, Wolk K, Schneider-Burrus S, Kalus S, Barbus S, Gomis-Kleindienst S, et al. Delayed diagnosis of hidradenitis suppurativa and its effect on patients and healthcare system. Dermatology 2020; 236: 421–430. DOI: https://doi.org/10.1159/000508787

Garg A, Neuren E, Cha D, Kirby JS, Ingram JR, Jemec GBE, et al. Evaluating patients’ unmet needs in hidradenitis suppurativa: results from the global survey of impact and healthcare needs (VOICE) project. J Am Acad Dermatol 2020; 82: 366–376. DOI: https://doi.org/10.1016/j.jaad.2019.06.1301

Published

2026-07-01

How to Cite

Moreira-Gomes, P., Costa, R., Granja, B., Azevedo, F., & Lisboa, C. (2026). Real-world Outcomes of Adalimumab in Hidradenitis Suppurativa: A 10-year Retrospective Longitudinal Study. Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0636

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Research letter

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