Injection-related Pain and the Benefit of a Syringe Pump for Dupilumab Adherence in Children with Atopic Dermatitis: a Retrospective Cross-sectional Study
DOI:
https://doi.org/10.2340/actadv.v106.adv-2026-0553Keywords:
atopic dermatitis, dupilumab, paediatrics, syringe pump, medical adherence, observational studyDownloads
References
Simpson EL, Lockshin B, Lee LW, Chen Z, Daoud M, Korotzer A. Real-world effectiveness of dupilumab in adult and adolescent patients with atopic dermatitis: 2-year interim data from the PROSE registry. Dermatol Ther 2024; 14: 261–270. DOI: https://doi.org/10.1007/s13555-023-01061-4
Lasek A, Bellon N, Mallet S, Puzenat E, Bursztejn AC, Abasq C, et al. Effectiveness and safety of dupilumab in the treatment of atopic dermatitis in children (6-11 years): data from a French multicentre retrospective cohort in daily practice. J Eur Acad Dermatol Venereol 2022; 36: 2423–2429. DOI: https://doi.org/10.1111/jdv.18450
Antalfy A, Berman K, Everitt C, Alten R, Latymer M, Godfrey CM. The adherence and outcomes benefits of using a connected, reusable auto-injector for self-injecting biologics: a narrative review. Adv Ther 2023; 40: 4758–4776. DOI: https://doi.org/10.1007/s12325-023-02671-2
Paller AS, Simpson EL, Siegfried EC, Cork MJ, Wollenberg A, Arkwright PD, et al. Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 2022; 400: 908–919. DOI: https://doi.org/10.1016/S0140-6736(22)01539-2
Song J, Taraban M, Yu YB, Lu L, Guha Biswas P, Xu W, et al. In-situ biophysical characterization of high-concentration protein formulations using w NMR. MAbs 2024; 16. DOI: https://doi.org/10.1080/19420862.2024.2304624
Berteau C, Filipe-Santos O, Wang T, Rojas HE, Granger C, Schwarzenbach F. Evaluation of the impact of viscosity, injection volume, and injection flow rate on subcutaneous injection tolerance. Med Devices (Auckl) 2015; 8: 473–484. DOI: https://doi.org/10.2147/MDER.S91019
van den Bemt BJF, Gettings L, Domańska B, Bruggraber R, Mountian I, Kristensen LE. A portfolio of biologic self-injection devices in rheumatology: how patient involvement in device design can improve treatment experience. Drug Deliv 2019; 26: 384–392. DOI: https://doi.org/10.1080/10717544.2019.1587043
Olsson M, Bajpai R, Wee LWY, Yew YW, Koh MJA, Thng S, et al. The cost of childhood atopic dermatitis in a multi-ethnic Asian population: a cost-of-illness study. Br J Dermatol 2020; 182: 1245–1252. DOI: https://doi.org/10.1111/bjd.18442
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