A Long Way to Diagnosis: Linear IgA Dermatosis Mimicking Prurigo Pigmentosa

Authors

  • Ann Giordano-Rosenbaum Department of Dermatology, University of Hamburg-Eppendorf, Hamburg, Germany https://orcid.org/0009-0007-5097-3096
  • Almut Böer-Auer Dermatologikum Hamburg, Hamburg, Germany
  • Enno Schmidt Lübeck Institute of Experimental Dermatology University of Lübeck, Lübeck, Germany; Department of Dermatology, University Clinic Schleswig-Holstein, Campus Lübeck, Lübeck, Germany
  • Christian Rose Department of Dermatology, University Clinic Schleswig-Holstein, Campus Lübeck, Lübeck, Germany; Dermatopathology Lübeck, Lübeck, Germany https://orcid.org/0000-0002-3882-1256

DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0686

Keywords:

autoimmune bullous dermatosis, dermatopathology, immunohistology, liner IgA bullous dermatosis, prurigo

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References

Schmidt E, Zillikens D. Pemphigoid diseases. Lancet 2013; 381: 320–332. DOI: https://doi.org/10.1016/S0140-6736(12)61140-4

Khan M, Park L, Skopit S. Management options for linear immunoglobulin A (IgA) bullous dermatosis: a literature review. Cureus 2023; 15: e36481. DOI: https://doi.org/10.7759/cureus.36481

Fortuna G, Marinkovich MP. Linear immunoglobulin A bullous dermatosis. Clin Dermatol 2012; 30: 38–50. DOI: https://doi.org/10.1016/j.clindermatol.2011.03.008

Caux F, Patsatsi A, Karakioulaki M, Antiga E, Baselga E, Borradori L, et al. S2k guidelines on diagnosis and treatment of linear IgA dermatosis initiated by the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol 2024; 38: 1006–1023. DOI: https://doi.org/10.1111/jdv.19880

Böer A, Misago N, Wolter M, Kiryu H, Wang XD, Ackerman AB. Prurigo pigmentosa: a distinctive inflammatory disease of the skin. Am J Dermatopathol 2003; 25: 117–129. DOI: https://doi.org/10.1097/00000372-200304000-00005

Saito M, Böer A, Ishiko A, Nishikawa T. Atypical dermatitis herpetiformis: a Japanese case that presented with initial lesions mimicking prurigo pigmentosa. Clin Exp Dermatol 2006; 31: 290–291. DOI: https://doi.org/10.1111/j.1365-2230.2005.02009.x

Michor-Tscharre C, D’Alì L, Cota C, Fink-Puches R, Cerroni L. Clinical and pathological spectrum of prurigo pigmentosa in central European individuals. JAMA Dermatol 2023; 159: 864–869. DOI: https://doi.org/10.1001/jamadermatol.2023.1917

Shimanovich I, Nitz JM, Witte M, Zillikens D, Rose C. Immunohistochemical diagnosis of mucous membrane pemphigoid. J Oral Pathol Med 2018; 47: 613–619. DOI: https://doi.org/10.1111/jop.12732

van Beek N, Holtsche MM, Atefi I, Olbrich H, Schmitz MJ, Pruessmann J, et al. State-of-the-art diagnosis of autoimmune blistering diseases. Front Immunol 2024; 15: 1363032. DOI: https://doi.org/10.3389/fimmu.2024.1363032

Kromminga A, Scheckenbach C, Georgi M, Hagel C, Arndt R, Christophers E, et al. Patients with bullous pemphigoid and linear IgA disease show a dual IgA and IgG autoimmune response to BP180. J Autoimmun 2000; 15: 293–300. DOI: https://doi.org/10.1006/jaut.2000.0437

Published

2026-09-07

How to Cite

Giordano-Rosenbaum, A., Böer-Auer, A., Schmidt, E., & Rose, C. (2026). A Long Way to Diagnosis: Linear IgA Dermatosis Mimicking Prurigo Pigmentosa. Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0686

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