A Rare Case of Minocycline-induced DIHS/DRESS with Predominant Pulmonary Involvement

Authors

  • Eriko Oiwa Department of Dermatology, JA Hiroshima General Hospital, 1-3-3 Jigozen, Hatsukaichi, Hiroshima 738-8503, Japan
  • Mayu Kanamoto Department of Dermatology, JA Hiroshima General Hospital, 1-3-3 Jigozen, Hatsukaichi, Hiroshima 738-8503, Japan
  • Hikari Sakamoto Department of Dermatology, JA Hiroshima General Hospital, 1-3-3 Jigozen, Hatsukaichi, Hiroshima 738-8503, Japan
  • Ibuki Uchino Department of Respiratory Medicine, JA Hiroshima General Hospital, 1-3-3 Jigozen, Hatsukaichi, Hiroshima 738-8503, Japan
  • Shunsuke Takahagi Department of Dermatology, JA Hiroshima General Hospital, 1-3-3 Jigozen, Hatsukaichi, Hiroshima 738-8503, Japan https://orcid.org/0000-0001-9951-1342

DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0829

Keywords:

DIHS, DRESS, minocycline, pulmonary involvement

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References

Hama N, Abe R, Gibson A, Phillips EJ. Drug-Induced Hypersensitivity Syndrome (DIHS)/Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis. J Allergy Clin Immunol Pract 2022; 10: 1155–1167. DOI: https://doi.org/10.1016/j.jaip.2022.02.004

Taweesedt PT, Nordstrom CW, Stoeckel J, Dumic I. Pulmonary Manifestations of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome: A Systematic Review. Biomed Res Int 2019; 2019: 1–10. DOI: https://doi.org/10.1155/2019/7863815

Mizukawa Y, Hama N, Niihara H, Miyagawa F, Hashizume H, Tohyama M, et al. Guidelines for the management of drug-induced hypersensitivity syndrome 2023. J Dermatol 2025; 52: e189–e209. DOI: https://doi.org/10.1111/1346-8138.17609

Calle AM, Aguirre N, Ardila JC, Cardona Villa R. DRESS syndrome: A literature review and treatment algorithm. World Allergy Organ J 2023; 16: 100673. DOI: https://doi.org/10.1016/j.waojou.2022.100673

Ogawa K, Morito H, Hasegawa A, Miyagawa F, Kobayashi N, Watanabe H, et al. Elevated serum thymus and activation-regulated chemokine (TARC/CCL17) relates to reactivation of human herpesvirus 6 in drug reaction with eosinophilia and systemic symptoms (DRESS)/drug-induced hypersensitivity syndrome (DIHS). Br J Dermatol 2014; 171: 425–427. DOI: https://doi.org/10.1111/bjd.12948

Naniwa T, Maeda S, Sawada H, Watanabe Y, Osawa T, Hayami Y, et al. Drug-induced hypersensitivity syndrome associated with a marked increase in anti-paramyxovirus antibody titers in a scleroderma patient. Allergol Int 2007; 56: 303–308. DOI: https://doi.org/10.2332/allergolint.C-06-49

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Published

2026-09-28

How to Cite

Oiwa, E., Kanamoto, M., Sakamoto, H., Uchino, I., & Takahagi, S. (2026). A Rare Case of Minocycline-induced DIHS/DRESS with Predominant Pulmonary Involvement. Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0829

Issue

Vol. 106 (2026)

Section

Short Communication

Categories

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