Molluscum Contagiosum, Warts and Condylomas during JAK Inhibitor Therapy for Atopic Dermatitis: a Retrospective Series of 17 Cases

Authors

  • Giuseppe Russo Department of Dermatology, Geneva university hospitals HUG, Genève, Suisse, Switzerland; Department of Dermatology, Saint-Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France https://orcid.org/0000-0003-3920-8055
  • Emmanuel Mahé Department of Dermatology, Hôpital Victor Dupuy, Argenteuil, France; Versailles-Saint-Quentin-en-Yvelines Unviersity, Montigny-le-Bretonneux, France
  • Florence Tetart Department of Dermatology and Allergology, CHU Rouen, Rouen, France
  • Audrey Loretan Department of Dermatology, Geneva university hospitals HUG, Genève, Suisse, Switzerland
  • Audrey Nosbaum Hospices Civils de Lyon, Department of allergy and Clinical Immunology, Centre Hospitalier Lyon Sud, Pierre-Bénite, France; CIRI, Centre International de Recherche en Infectiologie (Team Epidermal Immunity and Allergy Team), INSERM U1111, Université Lyon1, Ecole Normale Supérieure de Lyon, CNRS UMR 5308, Lyon, France
  • Marie Tauber Hospices Civils de Lyon, Department of allergy and Clinical Immunology, Centre Hospitalier Lyon Sud, Pierre-Bénite, France; CIRI, Centre International de Recherche en Infectiologie (Team Epidermal Immunity and Allergy Team), INSERM U1111, Université Lyon1, Ecole Normale Supérieure de Lyon, CNRS UMR 5308, Lyon, France
  • Nadia Raison-Peyron Department of Dermatology, Centre Hospitalier Universitaire Montpellier, Montpellier, France
  • Estelle Burle Department of Dermatology, CHU Toulouse-Larrey, Toulouse, France
  • Angèle Soria Sorbonne Université, Department of Dermatology and Allergology, Tenon Hospital, Assistance Publique-Hôpitaux de Paris, Paris, INSERM 1155, France
  • Emilie Brenaut Department of Dermatology, CHU de Brest, Brest, France
  • Anne Saussine Department of Dermatology, Saint-Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France
  • Thibault Mahévas Department of Dermatology, Saint-Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France
  • Jean-David Bouaziz Department of Dermatology, Saint-Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France
  • Emmanuel Laffitte Department of Dermatology, Geneva university hospitals HUG, Genève, Suisse, Switzerland
  • Marie Jachiet Department of Dermatology, Saint-Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France

DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0779

Keywords:

JAK inhibitors, molluscum contagiosum, warts, condyloma, atopic dermatitis, upadacitinib

Downloads

Download data is not yet available.

References

Jarneborn A, Kopparapu PK, Jin T. The Dual-Edged Sword: Risks and benefits Benefits of JAK inhibitors in infections. Pathogens 2025; 14: 324. DOI: https://doi.org/10.3390/pathogens14040324

Ireland PA, Verheyden M, Jansson N, Sebaratnam D, Sullivan J. Infection risk with JAK inhibitors in dermatoses: a meta-analysis. Int J Dermatol 2025; 64: 24–36. DOI: https://doi.org/10.1111/ijd.17501

Ravlo E, Ianevski A, Skipperstøen MN, Lysvand H, Schjølberg JO, Solheim O, et al. JAK inhibitors remove innate immune barriers facilitating viral propagation. NAR Mol Med 2025; 2: ugaf017. DOI: https://doi.org/10.1093/narmme/ugaf017

van der Gang LF, Atash K, Zuithoff NPA, Haeck I, Boesjes CM, Bacoş-Cosma OI, et al. Infection risk in atopic dermatitis patients treated with biologics and JAK inhibitors: BioDay results. J Eur Acad Dermatol Venereol 2025; 39: 2056–2068. DOI: https://doi.org/10.1111/jdv.20674

Kinoshita M, Ogawa Y, Kawamura T, Kirito K, Shimada S. Case of disseminated molluscum contagiosum caused by ruxolitinib, a Janus kinase 1 and 2 inhibitor. J Dermatol 2016; 43: 1387–1388. DOI: https://doi.org/10.1111/1346-8138.13404

Seale E, Gavigan G. Exacerbation of human papillomavirus infection with initiation of upadacitinib for atopic dermatitis. JAAD Case Rep 2023; 36: 60–62. DOI: https://doi.org/10.1016/j.jdcr.2023.04.019

Kennoki N, Nohata K, Nakamori Y. Impaired Human Papillomavirus (HPV) clearance in a patient on upadacitinib for atopic dermatitis: A case of refractory genital warts resolved after drug withdrawal. Cureus 2025; 17: e97974. DOI: https://doi.org/10.7759/cureus.97974

Takahashi N, Shimizu T, Kondoh A, Anzawa K, Shimizu A, Mabuchi T. Human Papilloma Virus Type 94-associated flat warts developing repeatedly during tofacitinib treatment: A case report and review. J Dermatol 2025. DOI: https://doi.org/10.1111/1346-8138.17814

Downloads

Published

2026-10-12

How to Cite

Russo, G., Mahé, E., Tetart, F., Loretan, A., Nosbaum, A., Tauber, M., … Jachiet, M. (2026). Molluscum Contagiosum, Warts and Condylomas during JAK Inhibitor Therapy for Atopic Dermatitis: a Retrospective Series of 17 Cases. Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0779

Issue

Vol. 106 (2026)

Section

Short Communication

Categories

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.

Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

Crossref
Scopus
Google Scholar
Europe PMC