Incidence, Prevalence and Diagnostic Delay in Pyoderma Gangrenosum: A Finnish Nationwide Registry-based Study

Authors

  • Suvi-Päivikk Sinikumpu Department of Dermatology, University Hospital of Oulu, Oulu, Finland and Medical Research Center, Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland https://orcid.org/0000-0001-6496-5475
  • Jari Jokelainen Northern Finland Birth Cohorts, Arctic Biobank, Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland https://orcid.org/0000-0003-4629-0560
  • Laura Huilaja Department of Dermatology, University Hospital of Oulu, Oulu, Finland and Medical Research Center, Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland https://orcid.org/0000-0002-7597-4323

DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0937

Keywords:

pyoderma gangrenosum, incidence, prevalence, epidemiology, diagnostic delay, dermatologists

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References

Langan SM, Groves RW, Card TR, Gulliford MC. Incidence, mortality, and disease associations of pyoderma gangrenosum in the United Kingdom: a retrospective cohort study. J Invest Dermatol 2012; 132: 2166–2170. DOI: https://doi.org/10.1038/jid.2012.130

Ruocco E, Sangiuliano S, Gravina AG, Miranda A, Nicoletti G. Pyoderma gangrenosum: an updated review. J Eur Acad Dermatol Venereol 2009; 23: 1008–1017. DOI: https://doi.org/10.1111/j.1468-3083.2009.03199.x

Shea M, Munoz EP, Kumar I, Zanet RA, Sengupta S, Ortega-Loayza AG. Prevalence of pyoderma gangrenosum: A systematic review and meta-regression ana Systematic Review and Meta-Regression Analysis. J Invest Dermatol 2025; 145: 3191–3195. DOI: https://doi.org/10.1016/j.jid.2025.05.030

Michelucci A, Capodici A, Granieri G, Manzo Margiotta F, Cei B, Marzano AV, et al. Trend in the diagnosis of pyoderma gangrenosum in Italy: A multicenter study. Dermatology 2026; 242: 137–144. DOI: https://doi.org/10.1159/000549357

Reese AM, Gupta AS, Latour E, Loyo M, Kaffenberger B, Creadore A, et al. Clinical characteristics and misdiagnosis of pyoderma gangrenosum of the head and neck: A retrospective study. J Am Acad Dermatol 2022; 87: 1130–1133. DOI: https://doi.org/10.1016/j.jaad.2022.02.008

Isoherranen K, O’Brien JJ, Barker J, Dissemond J, Hafner J, Jemec GBE, et al. Atypical wounds. Best clinical practice and challenges. J Wound Care 2019; 28: S1–S92. DOI: https://doi.org/10.12968/jowc.2019.28.Sup6.S1

Haddadin OM, Erickson KM, Latour E, Sisley J, Ortega-Loayza AG. Impact of delay of diagnosis of pyoderma gangrenosum on healing outcomes and health care utilization: A prospective cohort study. J Am Acad Dermatol 2024; 91: 1274–1277. DOI: https://doi.org/10.1016/j.jaad.2024.08.038

Taylor LT, Kody S, Rios-Duarte JA, Ortega-Loayza AG. Impact of diagnostic delay on patient perspectives in pyoderma gangrenosum: an online support group-based survey study. Arch Dermatol Res 2023; 315: 2737–2739. DOI: https://doi.org/10.1007/s00403-023-02685-4

Published

2026-10-20

How to Cite

Sinikumpu, S.-P., Jokelainen, J., & Huilaja, L. (2026). Incidence, Prevalence and Diagnostic Delay in Pyoderma Gangrenosum: A Finnish Nationwide Registry-based Study. Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0937

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Short Communication

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