Local Management of Anogenital Warts in Nonimmunocompromised Adults: A Network Metaanalysis of Randomized Controlled Trials

Authors

  • Réda Saib Department de Maladies-Infectieuses, Dermatologie, CHU de La Réunion, Saint Pierre, France https://orcid.org/0009-0001-4759-4462
  • Elisa Joly Department de Maladies-Infectieuses, Dermatologie, CHU de La Réunion, Saint Pierre, France
  • Sébastien Fouéré CeGIDD Saint-Louis, Fernand-Widal, Le Checkpoint, Hôpitaux Universitaires Saint-Louis, Lariboisière, Fernand-Widal, Assistance Publique des Hôpitaux de Paris, Paris, France
  • Christian Derancourt Cabinet libéral, 623 Rue du Barry, 05130 Tallard, France
  • Babacar Tounkara Inserm CICEC 1410, La Réunion, Saint-Pierre, France
  • Cyril Ferdynus Inserm CICEC 1410, La Réunion, Saint-Pierre, France
  • Antoine Bertolotti Department de Maladies-Infectieuses, Dermatologie, CHU de La Réunion, Saint Pierre, France; Inserm CICEC 1410, La Réunion, Saint-Pierre, France

DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0435

Keywords:

HPV specialist, condyloma specialist, systematic review, RCT, Condyloma, Efficacy

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References

Haute Autorité de Santé. Therapeutic management of patients with anogenital warts. 2024. Available from: https://www.has-sante.fr/upload/docs/application/pdf/2024-11/prise_en_charge_therapeutique_des_patients_atteints_de_condylomes_ano-genitaux_-_recommandations.pdf

Gilson R, Nugent D, Werner RN, Ballesteros J, Ross J. 2019 IUSTI‐Europe guideline for the management of anogenital warts. Acad Dermatol Venereol 2020; 34: 1644–1653. DOI: https://doi.org/10.1111/jdv.16522

Bertolotti A, Ferdynus C, Milpied B, Dupin N, Huiart L, Derancourt C. Local management of anogenital warts in non-immunocompromised adults: a network meta-analysis of randomized controlled trials. Dermatol Ther 2020; 10: 249–262. DOI: https://doi.org/10.1007/s13555-020-00357-z

Barton S, Wakefield V, O’Mahony C, Edwards S. Effectiveness of topical and ablative therapies in treatment of anogenital warts: a systematic review and network meta-analysis. BMJ Open 2019; 9: e027765. DOI: https://doi.org/10.1136/bmjopen-2018-027765

Jung JM, Jung CJ, Lee WJ, Won CH, Lee MW, Choi JH, et al. Topically applied treatments for external genital warts in nonimmunocompromised patients: a systematic review and network meta-analysis. Br J Dermatol 2020; 183: 24–36. DOI: https://doi.org/10.1111/bjd.18638

Saib R, Joly E, Fouere S, Derancourt C, Tounkara B, Ferdynus C, et al. Adverse effects of treatments for anogenital warts in non-immunocompromised adults: a network meta-analysis of randomized controlled trials. Dermatol Ther 2026; 16: 4325–4340. DOI: https://doi.org/10.1007/s13555-026-01857-0

Werner RN, Westfechtel L, Dressler C, Nast A. Self-administered interventions for anogenital warts in immunocompetent patients: a systematic review and meta-analysis. Sex Transm Infect 2017; 93: 155–161. DOI: https://doi.org/10.1136/sextrans-2016-052768

Agbeci H, Rollot O, Derancourt C, Baglione Q, Benard A, Bertolotti A. Health economic evaluation of topical treatments for external anogenital warts. Ann Dermatol Venereol 2024; 151: 103288. DOI: https://doi.org/10.1016/j.annder.2024.103288

Additional Files

Published

2026-10-21

How to Cite

Saib, R., Joly, E., Fouéré, S., Derancourt, C., Tounkara, B., Ferdynus, C., & Bertolotti, A. (2026). Local Management of Anogenital Warts in Nonimmunocompromised Adults: A Network Metaanalysis of Randomized Controlled Trials. Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0435

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Section

Research letter

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