Rapid Enlargement of Vitiligo Vulgaris after Initiation of Dupilumab for Atopic Dermatitis: A Case Report
DOI:
https://doi.org/10.2340/actadv.v101.545Keywords:
atopic dermatitis, vitiligo vulgaris, dupilumab, interleukin-4, interleukin-13Abstract
Abstract is missing (Short communication)
Downloads
References
Simpson EL, Bieber T, Guttman-Yassky E, Beck LA, Blauvelt A, Cork MJ, et al. Two phase 3 trials of dupilumab versus placebo in atopic dermatitis. N Engl J Med 2016; 375: 2335-2348.
https://doi.org/10.1056/NEJMoa1610020 DOI: https://doi.org/10.1056/NEJMoa1610020
Uchida H, Kamata M, Mizukawa I, Watanabe A, Agematsu A, Nagata M, et al. Real-world effectiveness and safety of dupilumab for the treatment of atopic dermatitis in Japanese patients: a single-centre retrospective study. Br J Dermatol 2019; 181: 1083-1085.
https://doi.org/10.1111/bjd.18163 DOI: https://doi.org/10.1111/bjd.18163
Uchida H, Kamata M, Kato A, Mizukawa I, Watanabe A, Agematsu A, et al. One-year real-world clinical effectiveness, safety, and laboratory safety of dupilumab in Japanese adult patients with atopic dermatitis: a single-center retrospective study. J Am Acad Dermatol 2021; 84: 547-550.
https://doi.org/10.1016/j.jaad.2020.05.102 DOI: https://doi.org/10.1016/j.jaad.2020.05.102
Wańkowicz-Kalińska A, van den Wijngaard RM, Tigges BJ, Westerhof W, Ogg GS, Cerundolo V, et al. Immunopolarization of CD4+ and CD8+ T cells to type-1-like is associated with melanocyte loss in human vitiligo. Lab Invest 2003; 83: 683-695.
https://doi.org/10.1097/01.LAB.0000069521.42488.1B DOI: https://doi.org/10.1097/01.LAB.0000069521.42488.1B
Yang L, Wei Y, Sun Y, Shi W, Yang J, Zhu L, et al. Interferon-gamma inhibits melanogenesis and induces apoptosis in melanocytes: a pivotal role of CD8+ cytotoxic t lymphocytes in vitiligo. Acta Derm Venereol 2015; 95: 664-670.
https://doi.org/10.2340/00015555-2080 DOI: https://doi.org/10.2340/00015555-2080
Cheuk S, Schlums H, Gallais Sérézal I, Martini E, Chiang SC, Marquardt N, et al. CD49a expression defines tissue-resident CD8(+) T cells poised for cytotoxic function in human skin. Immunity 2017; 46: 287-300.
https://doi.org/10.1016/j.immuni.2017.01.009 DOI: https://doi.org/10.1016/j.immuni.2017.01.009
Kanda N, Koto M, Hoashi T, Saeki H. Case of alopecia areata during dupilumab treatment for atopic dermatitis. J Dermatol 2019; 46: e332-e333.
https://doi.org/10.1111/1346-8138.14880 DOI: https://doi.org/10.1111/1346-8138.14880
Maloney NJ, Worswick S, Cheng K. Development of alopecia in patients treated with dupilumab. Dermatol Ther 2019; 32: e12869.
https://doi.org/10.1111/dth.12869 DOI: https://doi.org/10.1111/dth.12869
Ständer S, Trense Y, Thaçi D, Ludwig RJ. Alopecia areata development in atopic dermatitis patients treated with dupilumab. J Eur Acad Dermatol Venereol 2020; 34: e612-e613.
https://doi.org/10.1111/jdv.16493 DOI: https://doi.org/10.1111/jdv.16493
Ito T, Kageyama R, Nakazawa S, Honda T. Understanding the significance of cytokines and chemokines in the pathogenesis of alopecia areata. Exp Dermatol 2020; 29: 726-732.
https://doi.org/10.1111/exd.14129 DOI: https://doi.org/10.1111/exd.14129
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2021 Shintaro Takeoka, Masahiro Kamata, Ikumi Yokoi, Aya Takehara, Yayoi Tada
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.
