Lectin-binding sites in squamous cell carcinomas and keratoacanthomas
DOI:
https://doi.org/10.2340/0001555568480485Abstract
The lectin-binding pattern of malignant and benign human epidermal tumours was studied. Twelve squamous cell carcinomas and ten kerato-acanthomas were investigated, using fluorochrome-conjugated lectins. Lectins used were Canavalia ensiformis agglutinin (Con-A), Helix pomatia agglutinin (HPA), Phaseolus vulgaris agglutinin (PHA-L), and Ricinus communis agglutinin (RCA-120). Two types of fluorescence pattern, Intercellular ´Pemphigus-like´ and Peritumoral, were noted. Both allowed classification of these tumours on the basis of their lectin-binding reactivity. Moreover, the expression of receptors for these lectins made it possible to distinguish between low-grade and well-differentiated squamous cell carcinomas.Downloads
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Published
1988-11-01
How to Cite
Ramírez-Bosca, A., Reano, A., Valcuende-Cavero, F., Thivolet, J., & Castells-Rodellas, A. (1988). Lectin-binding sites in squamous cell carcinomas and keratoacanthomas. Acta Dermato-Venereologica, 68(6), 480–485. https://doi.org/10.2340/0001555568480485
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