Vulvovaginal-gingival Lichen Planus: Association with Lichen Planopilaris and Stratified Epithelium-specific Antinuclear Antibodies

Authors

  • Malgorzata Olszewska
  • Agnieszka Banka-Wrona
  • Anna Skrok
  • Adriana Rakowska
  • Renata Górska
  • Lynn W. Solomon
  • Lidia Rudnicka

DOI:

https://doi.org/10.2340/00015555-2141

Abstract

Vulvovaginal-gingival lichen planus (VVG-LP) consists of a triad of symptoms: vulval, vaginal and gingival lichen planus lesions. The aim of this study was to analyse the prevalence of lesions in various anatomical locations in patients with VVG-LP. The study included 126 consecutive patients with lichen planus. Sixteen (12.7%) patients fulfilled the criteria of VVG-LP. In 12/16 (75%) patients with VVG-LP scalp lesions were also observed. Stratified epithelium-specific antinuclear antibodies (SES-ANA) and anti-ΔNp.3α antibodies were detected in 10/16 (75%) patients with VVG-LP and in 15/110 (13.6%) patients with other forms of lichen planus (p < 0.05). In conclusion, VVG-LP is frequently associated with lichen planopilaris. The new entity may be termed "vulvovaginal-gingival-pilar lichen planus" and our study indicates that SES-ANA is a marker of this type of lichen planus with extensive, severe and refractory-to-therapy involvement of the mucous membranes, skin and scalp.

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Published

2015-07-07

How to Cite

Olszewska, M., Banka-Wrona, A., Skrok, A., Rakowska, A., Górska, R., Solomon, L. W., & Rudnicka, L. (2015). Vulvovaginal-gingival Lichen Planus: Association with Lichen Planopilaris and Stratified Epithelium-specific Antinuclear Antibodies. Acta Dermato-Venereologica, 96(1), 92–96. https://doi.org/10.2340/00015555-2141

Issue

Vol. 96 No. 1 (2016)

Section

Articles

License

Copyright (c) 2015 Malgorzata Olszewska, Agnieszka Banka-Wrona, Anna Skrok, Adriana Rakowska, Renata Górska, Lynn W. Solomon, Lidia Rudnicka

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

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