PUVA therapy for photosensitive psoriasis

Authors

  • AM Ros
  • Wennersten G.

DOI:

https://doi.org/10.2340/0001555567501505

Abstract

The purpose of this study was to assess the prophylactic effect of oral photochemotherapy with psoralens and UVA (PUVA) on patients with light-sensitive psoriasis. Of fifteen patients with photosensitive psoriasis, ten with a history of polymorphous light eruption (PMLE) slowly developing into psoriasis were treated with trimethylpsoralen (TMP) and UVA. Five patients with no preceding PMLE reaction were similarly treated; two with 8-methoxypsoralen (8-MOP), two with TMP and one in whom 8-MOP was later changed to TMP. Good to excellent results were obtained in 9/10 of the first category and in 3/5 of the second, giving an overall efficacy of 80%. Preexisting psoriatic lesions did not, however, heal during TMP therapy but did so when treated with 8-MOP. The results confirm, for light-sensitive psoriatics, the efficacy of PUVA in photosensitive disorders.

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Published

1987-11-01

How to Cite

Ros, A., & Wennersten G. (1987). PUVA therapy for photosensitive psoriasis. Acta Dermato-Venereologica, 67(6), 501–505. https://doi.org/10.2340/0001555567501505

Issue

Section

Articles