Single exposure to ultraviolet irradiation and elicitation of human allergic contact dermatitis
DOI:
https://doi.org/10.2340/00015555659396Abstract
Ultraviolet radiation has been stated to inhibit afferent as well as efferent phases of allergic contract dermatitis. In this controlled study 17 female patients with nickel allergy were studied by three different protocols after an initial determination of their degree of hypersensitivity. They were patch tested with nickel sulfate immediately after UVB, 4-6 days after UVB, or immediately after external PUVA. Neither depressing nor enhancing of the allergic reaction was observed when compared to non-irradiated controls. The role of Langerhans cells as antigen-presenting cell playing an important role in the elicitation phase of allergic contract dermatitis is discussed and questioned.Downloads
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Copyright (c) 1985 Acta Dermato-VenereologicaAll digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
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