Lambert-Eaton Myasthenic Syndrome and Paraneoplastic Cerebellar Degeneration Associated with Merkel Cell Carcinoma with Unknown Primary: A Case Report

Authors

  • Andrea Agostini Department of Medical Sciences and Human Oncology, Section of Dermatology, University of Turin, Via Cherasco 23, IT-12124 Torino, Italy
  • Martina Merli
  • Gianluca Avallone
  • Lorenza Burzi
  • Luca Mastorino
  • Mattia Parisi
  • Davide Bertuzzo
  • Bruno Ferrero
  • Marzia Cerrato
  • Serena Badellino
  • Luca Molinaro
  • Leonardo Lopiano
  • Simone Ribero
  • Pietro Quaglino

DOI:

https://doi.org/10.2340/00015555-3798

Keywords:

skin neoplasm, oncology, carcinoma, Merkel cell, Lambert-Eaton myasthenic syndrome

Abstract

Abstract is missing (Short communication)

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References

Bichakjian CK, Olencki T, Aasi SZ, Alam M, Andersen JS, Blitzblau R, et al. Merkel cell carcinoma, version 1.2018, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw 2018; 16: 742-774.

DOI: https://doi.org/10.6004/jnccn.2018.0055

Iyer JG, Parvathaneni K, Bhatia S, Tarabadkar ES, Blom A, Doumani R, et al. Paraneoplastic syndromes (PNS) associated with Merkel cell carcinoma (MCC): a case series of 8 patients highlighting different clinical manifestations. J Am Acad Dermatol 2016; 75: 541-547.

DOI: https://doi.org/10.1016/j.jaad.2016.04.040

Simmons DB, Duginski TM, McClean JC, Amato AA, Sladky JH. Lambert-Eaton myasthenic syndrome and Merkel cell carcinoma. Muscle Nerve 2016; 53: 325-326.

DOI: https://doi.org/10.1002/mus.24934

Nguyen ND, Simmons DB, Bersabe AR, Duginski TM, Sladky JH, Walton D, et al. Lambert-Eaton myasthenic syndrome and Merkel cell carcinoma. Cutis 2019; 103: E19-E23.

Sharobeam A, Ray J, Dong J, Chong V. Subacute cerebellar degeneration due to a paraneoplastic phenomenon associated with metastatic Merkel cell carcinoma: a case report. Case Rep Oncol 2017; 10: 764-768.

DOI: https://doi.org/10.1159/000479731

Queen D, Gu Y, Lopez A, Chen D, Geskin LJ. Paraneoplastic cerebellar ataxia in Merkel cell carcinoma of unknown primary. JAAD Case Rep 2019; 5: 398-400.

DOI: https://doi.org/10.1016/j.jdcr.2019.02.004

Pavolucci L, Giannini G, Giannoccaro MP, Foschini MP, Lang B, Avoni P, et al. Paraneoplastic cerebellar degeneration and Lambert-Eaton myasthenia in a patient with Merkel cell carcinoma and voltage-gated calcium channel antibodies. Muscle Nerve 2017; 56: 998-1000.

DOI: https://doi.org/10.1002/mus.25530

Lawrence LEB, Saleem A, Sahoo MK, Tan SK, Pinsky BA, Natkunam Y, et al. Is Merkel cell carcinoma of lymph node actually metastatic cutaneous Merkel cell carcinoma? Am J Clin Pathol 2020; 154: 369-380.

DOI: https://doi.org/10.1093/ajcp/aqaa051

Naseri S, Steiniche T, Ladekarl M, Bønnelykke-Behrndtz ML, Hölmich LR, Langer SW, et al. Management recommendations for Merkel cell carcinoma - a Danish perspective. Cancers (Basel) 2020; 12: 554.

DOI: https://doi.org/10.3390/cancers12030554

Published

2021-05-10

How to Cite

Agostini, A., Merli, M., Avallone, G., Burzi, L., Mastorino, L., Parisi, M., … Quaglino, P. (2021). Lambert-Eaton Myasthenic Syndrome and Paraneoplastic Cerebellar Degeneration Associated with Merkel Cell Carcinoma with Unknown Primary: A Case Report. Acta Dermato-Venereologica, 101(5), adv00452. https://doi.org/10.2340/00015555-3798

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Short Communication

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