Interleukin-17 and - 23 Inhibitors Associated with Direct Effects on Depressive Symptoms in Psoriasis: Results from a Register Study

Authors

  • Axel Svedbom Division of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Mona Ståhle Division of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

DOI:

https://doi.org/10.2340/actadv.v103.7138

Keywords:

Psoriasis, Depression, Biologics, Systemic Inflammation

Abstract

Abstract is missing (Short communication)

Downloads

Download data is not yet available.

References

Kleyn CE, Talbot PS, Mehta NN, Sampogna F, Bundy C, Ashcroft DM, et al. Psoriasis and mental health workshop report: exploring the links between psychosocial factors, psoriasis, neuroinflammation and cardiovascular disease risk. Acta Derm Venereol 2020; 100: adv00020.

https://doi.org/10.2340/00015555-3375 DOI: https://doi.org/10.2340/00015555-3375

Tee SI, Lim ZV, Theng CT, Chan KL, Giam YC. A prospective cross-sectional study of anxiety and depression in patients with psoriasis in Singapore. J Eur Acad Dermatol Venereol 2016; 30: 1159-1164.

https://doi.org/10.1111/jdv.13615 DOI: https://doi.org/10.1111/jdv.13615

Reich A, Mędrek K, Szepietowski JC. Interplay of itch and psyche in psoriasis: an update. Acta Derm Venereol 2016; 96: 55-57.

https://doi.org/10.2340/00015555-2433

Koo J, Marangell LB, Nakamura M, Armstrong A, Jeon C, Bhutani T, et al. Depression and suicidality in psoriasis: review of the literature including the cytokine theory of depression. J Eur Acad Dermatol Venereol 2017; 31: 1999-2009.

https://doi.org/10.1111/jdv.14460 DOI: https://doi.org/10.1111/jdv.14460

Wang X, Li Y, Wu L, Xiao S, Ji Y, Tan Y, et al. Dysregulation of the gut-brain-skin axis and key overlapping inflammatory and immune mechanisms of psoriasis and depression. Biomed Pharmacother 2021; 137: 111065.

https://doi.org/10.1016/j.biopha.2020.111065 DOI: https://doi.org/10.1016/j.biopha.2020.111065

Zafiriou E, Daponte AI, Siokas V, Tsigalou C, Dardiotis E, Bogdanos DP. Depression and obesity in patients with psoriasis and psoriatic arthritis: Is IL-17-mediated immune dysregulation the connecting link? Front Immunol 2021; 12: 699848.

https://doi.org/10.3389/fimmu.2021.699848 DOI: https://doi.org/10.3389/fimmu.2021.699848

Svedbom A, Ståhle M. Real-world comparative effectiveness of adalimumab, etanercept and methotrexate: a Swedish register analysis. J Eur Acad Dermatol Venereol 2020; 34: 525-532.

https://doi.org/10.1111/jdv.15978 DOI: https://doi.org/10.1111/jdv.15978

Svanborg P, Asberg M. A new self-rating scale for depression and anxiety states based on the Comprehensive Psychopathological Rating Scale. Acta Psychiatr Scand 1994; 89: 21-28.

https://doi.org/10.1111/j.1600-0447.1994.tb01480.x DOI: https://doi.org/10.1111/j.1600-0447.1994.tb01480.x

Oppe M, Devlin NJ, Szende A. EQ-5D value sets: inventory, comparative review and user guide. Springer, Berlin, Germany; 2007.

Fredriksson T, Pettersson U. Severe psoriasis - oral therapy with a new retinoid. Dermatologica 1978; 157: 238-244.

https://doi.org/10.1159/000250839 DOI: https://doi.org/10.1159/000250839

Reich A, Riepe C, Anastasiadou Z, Mędrek K, Augustin M, Szepietowski JC, et al. Itch assessment with visual analogue scale and numerical rating scale: determination of minimal clinically important difference in chronic itch. Acta Derm Venereol 2016; 96: 978-980.

https://doi.org/10.2340/00015555-2433 DOI: https://doi.org/10.2340/00015555-2433

Dominguez PL, Husni ME, Holt EW, Tyler S, Qureshi AA. Validity, reliability, and sensitivity-to-change properties of the psoriatic arthritis screening and evaluation questionnaire. Arch Dermatol Res 2009; 301: 573-579.

https://doi.org/10.1007/s00403-009-0981-3 DOI: https://doi.org/10.1007/s00403-009-0981-3

Finlay AY, Khan G. Dermatology Life Quality Index (DLQI) - a simple practical measure for routine clinical use. Clin Exp Dermatol 1994; 19: 210-216.

https://doi.org/10.1111/j.1365-2230.1994.tb01167.x DOI: https://doi.org/10.1111/j.1365-2230.1994.tb01167.x

Hengartner MP, Plöderl M. Estimates of the minimal important difference to evaluate the clinical significance of antidepressants in the acute treatment of moderate-to-severe depression. BMJ Evid Based Med 2022; 27: 69-73.

https://doi.org/10.1136/bmjebm-2020-111600 DOI: https://doi.org/10.1136/bmjebm-2020-111600

Published

2023-08-16

How to Cite

Svedbom, A., & Ståhle, M. (2023). Interleukin-17 and - 23 Inhibitors Associated with Direct Effects on Depressive Symptoms in Psoriasis: Results from a Register Study. Acta Dermato-Venereologica, 103, adv7138. https://doi.org/10.2340/actadv.v103.7138

Funding data