Real-life Use of Bexarotene for T-cell Cutaneous Lymphoma Management: Efficacy and Tolerance with Low Doses

Authors

  • Jacques Rouanet Dermatology and Oncodermatology Department, CHU Clermont-Ferrand, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France
  • Ines Joulie Dermatology and Oncodermatology Department, CHU Clermont-Ferrand, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France
  • Celine Lambert DRCI, Biostatistics Unit, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France
  • Michel D'Incan Dermatology and Oncodermatology Department, CHU Clermont-Ferrand, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France

DOI:

https://doi.org/10.2340/actadv.v102.718

Keywords:

bexarotene, T-cell cutaneous lymphoma, mycosis fungoides, Sezary syndrome, depression

Abstract

Abstract is missing (Short communication)

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References

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https://doi.org/10.1182/blood-2018-11-881268 DOI: https://doi.org/10.1182/blood-2018-11-881268

Duvic M, Hymes K, Heald P, Breneman D, Martin AG, Myskowski P, et al. Bexarotene is effective and safe for treatment of refractory advanced-stage cutaneous T-cell lymphoma: multinational phase II-III trial results. J Clin Oncol 2001; 19: 2456-2471.

https://doi.org/10.1200/JCO.2001.19.9.2456 DOI: https://doi.org/10.1200/JCO.2001.19.9.2456

Sokolowska-Wojdylo M, Florek A, Zaucha JM, Chmielowska E, Giza A, Knopinska-Posluszny W, et al. Polish Lymphoma Research Group experience with bexarotene in the treatment of cutaneous t-cell lymphoma. Am J Ther 2016; 23: e749-756.

https://doi.org/10.1097/MJT.0000000000000056 DOI: https://doi.org/10.1097/MJT.0000000000000056

Quereux G, Saint-Jean M, Peuvrel L, Brocard A, Knol AC, Dreno B. Bexarotene in cutaneous T-cell lymphoma: third retrospective study of long-term cohort and review of the literature. Expert Opin Pharmacother 2013; 14: 1711-1721.

https://doi.org/10.1517/14656566.2013.810718 DOI: https://doi.org/10.1517/14656566.2013.810718

Väkevä L, Ranki A, Hahtola S. Ten-year experience of bexarotene therapy for cutaneous T-cell lymphoma in Finland. Acta Derm Venereol 2012; 92: 258-263.

https://doi.org/10.2340/00015555-1359 DOI: https://doi.org/10.2340/00015555-1359

Abbott RA, Whittaker SJ, Morris SL, Russell-Jones R, Hung T, Bashir SJ, et al. Bexarotene therapy for mycosis fungoides and Sezary syndrome. Br J Dermatol 2009; 160: 1299-1307.

https://doi.org/10.1111/j.1365-2133.2009.09037.x DOI: https://doi.org/10.1111/j.1365-2133.2009.09037.x

Roche Gamon E, Perez Ferriols A, Vilata Corell JJ, Alegre de Miquel V. [Mycosis fungoid treated with oral bexarotene: study of 13 cases]. Med Clin (Barc) 2007; 129: 677 (in Spanish).

https://doi.org/10.1157/13112095 DOI: https://doi.org/10.1157/13112095

Fujimura T, Sato Y, Tanita K, Amagai R, Shimauchi T, Ogata D, et al. Case series of cutaneous T-cell lymphomas treated with bexarotene-based therapy. J Dermatol 2020; 47: 636-640.

https://doi.org/10.1111/1346-8138.15322 DOI: https://doi.org/10.1111/1346-8138.15322

Gniadecki R, Assaf C, Bagot M, Dummer R, Duvic M, Knobler R, et al. The optimal use of bexarotene in cutaneous T-cell lymphoma. Br J Dermatol 2007; 157: 433-440.

https://doi.org/10.1111/j.1365-2133.2007.07975.x DOI: https://doi.org/10.1111/j.1365-2133.2007.07975.x

Published

2022-07-07

How to Cite

Rouanet, J., Joulie, I., Lambert, C., & D’Incan, M. (2022). Real-life Use of Bexarotene for T-cell Cutaneous Lymphoma Management: Efficacy and Tolerance with Low Doses. Acta Dermato-Venereologica, 102, adv00746. https://doi.org/10.2340/actadv.v102.718

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