The genetics of vitiligo

Authors

  • M. Hafez
  • L. Sharaf
  • SM. Abd el-Nabi

DOI:

https://doi.org/10.2340/0001555563249251

Abstract

The genetics of vitiligo has been studied in 150 probands and their families. A familial concentration of the disease has been demonstrated which supports the concept that hereditary factors contribute to the etiology of vitiligo. Segregation analysis was not consistent with inheritance at a single autosomal or x-linked locus. Further analysis suggested that vitiligo is determined by multifactorial inheritance. An estimate of heritability of liability was found to be 72.4%, indicating that genetic factors play a significant role in the etiology.

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Published

1983-05-01

How to Cite

Hafez, M., Sharaf, L., & Abd el-Nabi, S. (1983). The genetics of vitiligo. Acta Dermato-Venereologica, 63(3), 249–251. https://doi.org/10.2340/0001555563249251

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Section

Articles