Monocyte Fc-IgG receptors expression and soluble suppressor factor in skin squamous cell carcinoma

Authors

  • GA. Vena
  • G. Angelini
  • R. D´Ovidio
  • A. Pastore
  • CL. Meneghini

DOI:

https://doi.org/10.2340/0001555563507512

Abstract

The expression of Fc-IgG receptors on mononuclear phagocytes (monocytes/macrophages), as well as the activity of soluble immune suppressor supernatant of T-cell proliferation (SISS-T) factor have been investigated in 23 patients with squamous cell carcinoma (SCC) of the lower lip, including 8 patients with metastases in the regional lymph glands. The results demonstrated a significant increase of the expression of Fc-IgG receptors only on circulating monocytes of patients with metastatic SCC. The suppressor function evaluated by means of the SISS-T factor proved normal in patients with nonmetastatic skin SCC and reduced in 8 patients with metastatic SCC.

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Published

1983-11-01

How to Cite

Vena, G., Angelini, G., D´Ovidio, R., Pastore, A., & Meneghini, C. (1983). Monocyte Fc-IgG receptors expression and soluble suppressor factor in skin squamous cell carcinoma. Acta Dermato-Venereologica, 63(6), 507–512. https://doi.org/10.2340/0001555563507512

Issue

Section

Articles