Sebaceous glands changes following topical application of citral

Authors

  • A. Abramovici
  • R. Wolf
  • M. Sandbank

DOI:

https://doi.org/10.2340/0001555563428431

Abstract

The long-lasting effect of a flavour cosmetic constituent on male rat skin was studied. Topical daily application of citral (15.4%) solution for 3 months produced an increase in the number of sebaceous gland lobules and hyperplasia of sebaceous cells in each gland. It is suggested that the mechanism of this hyperplasia might be activation of the testosterone 5 alpha-reductase which induces the formation of dihydrotestosterone, the mediator of sebaceous gland activity.

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Published

1983-09-01

How to Cite

Abramovici, A., Wolf, R., & Sandbank, M. (1983). Sebaceous glands changes following topical application of citral. Acta Dermato-Venereologica, 63(5), 428–431. https://doi.org/10.2340/0001555563428431

Issue

Section

Articles