Trousseau Syndrome in a Case of Extramammary Paget’s Disease

Authors

  • Megumi Fujimoto Department of Dermatology, Osaka University Graduate School of Medicine, Osaka, Japan
  • Yosuke Ishitsuka Department of Dermatology, Osaka University Graduate School of Medicine, Osaka, Japan
  • Atsushi Tanemura Department of Dermatology, Osaka University Graduate School of Medicine, Osaka, Japan
  • Satoshi Nojima Department of Pathology, Osaka University Graduate School of Medicine, Osaka, Japan
  • Manabu Fujimoto Department of Dermatology, Osaka University Graduate School of Medicine, Osaka, Japan

DOI:

https://doi.org/10.2340/actadv.v103.9405

Keywords:

Extramammary Paget's disease,, Cancer-associated hypercoagulable state

Abstract

Abstract is missing (Short communication)

Downloads

Download data is not yet available.

References

O'Donnell JS, Teng MWL, Smyth MJ. Cancer immunoediting and resistance to T cell-based immunotherapy. Nat Rev Clin Oncol 2019; 16: 151-167.

https://doi.org/10.1038/s41571-018-0142-8 DOI: https://doi.org/10.1038/s41571-018-0142-8

Kibbi N, Owen JL, Worley B, Wang JX, Harikumar V, Downing MB, et al. Evidence-based clinical practice guidelines for extramammary Paget disease. JAMA Oncol 2022; 8: 618-628.

https://doi.org/10.1001/jamaoncol.2021.7148 DOI: https://doi.org/10.1001/jamaoncol.2021.7148

Banno A, Chiba K, Kasai H, Nagami K. Ante-mortem diagnosis of pulmonary tumour thrombotic microangiopathy in a patient with unrecognised extramammary Paget's disease. BMJ Case Rep 2016; 2016:bcr2016216666.

https://doi.org/10.1136/bcr-2016-216666 DOI: https://doi.org/10.1136/bcr-2016-216666

Teruya H, Mukaigawara M, Hirata K. Progressive dyspnea in a woman with genital skin lesions. JAMA Oncol 2020; 6: 433-434.

https://doi.org/10.1001/jamaoncol.2019.5863 DOI: https://doi.org/10.1001/jamaoncol.2019.5863

Kato A, Kato H, Komori S, Nakano S, Murase T, Nakamura M, et al. Pulmonary tumor thrombotic microangiopathy secondary to extramammary Paget's disease: an autopsy case report and literature review. Case Rep Oncol 2021; 14: 1328-1332.

https://doi.org/10.1159/000515262 DOI: https://doi.org/10.1159/000515262

Oyama Y, Nishida H, Kondo Y, Kusaba T, Kadowaki H, Harada T, et al. Pulmonary tumor thrombotic microangiopathy associated with extramammary Paget's disease: An autopsy case report. Pathol Int 2020; 70: 680-685.

https://doi.org/10.1111/pin.12980 DOI: https://doi.org/10.1111/pin.12980

Wahrenbrock M, Borsig L, Le D, Varki N, Varki A. Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas. J Clin Invest 2003; 112: 853-862.

https://doi.org/10.1172/JCI200318882 DOI: https://doi.org/10.1172/JCI200318882

Ren R, Yan H, Gui Y, Zhao J, Wang H, Ji D, et al. Clinical features of trousseau syndrome with cerebral infarction as the initial manifestation. Neurologist 2020; 25: 117-121.

https://doi.org/10.1097/NRL.0000000000000275 DOI: https://doi.org/10.1097/NRL.0000000000000275

Hatta N, Yamada M, Hirano T, Fujimoto A, Morita R. Extramammary Paget's disease: treatment, prognostic factors and outcome in 76 patients. Br J Dermatol 2008; 158: 313-318.

https://doi.org/10.1111/j.1365-2133.2007.08314.x DOI: https://doi.org/10.1111/j.1365-2133.2007.08314.x

Sawamura S, Kajihara I, Tasaki Y, Otsuka-Maeda S, Sakamoto R, Kanazawa-Yamada S, et al. Overexpression of MUC16 (CA125) in extramammary Paget's disease. Jpn J Clin Oncol 2020; 50: 1330-1332.

https://doi.org/10.1093/jjco/hyaa154 DOI: https://doi.org/10.1093/jjco/hyaa154

Hata H, Abe R, Hoshina D, Saito N, Homma E, Aoyagi S, et al. MUC5AC expression correlates with invasiveness and progression of extramammary Paget's disease. J Eur Acad Dermatol Venereol 2014; 28: 727-732.

https://doi.org/10.1111/jdv.12156 DOI: https://doi.org/10.1111/jdv.12156

Kato H, Nakamura M, Watanabe S, Oda T, Morita A. Combined serum carcinoembryonic antigen and cytokeratin 19 fragment levels provide a sensitive biomarker for lymph node metastasis in extramammary Paget's disease. J Dermatol 2020; 47: 763-769.

https://doi.org/10.1111/1346-8138.15392 DOI: https://doi.org/10.1111/1346-8138.15392

Haridas D, Ponnusamy MP, Chugh S, Lakshmanan I, Seshacharyulu P, Batra SK. MUC16: molecular analysis and its functional implications in benign and malignant conditions. Faseb J 2014; 28: 4183-4199.

https://doi.org/10.1096/fj.14-257352 DOI: https://doi.org/10.1096/fj.14-257352

Ellis R, Tang D, Nasr B, Greenwood A, McConnell A, Anagnostou ME, et al. Epidermal autophagy and beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I melanomas. Br J Dermatol 2020; 182: 156-165.

https://doi.org/10.1111/bjd.18086 DOI: https://doi.org/10.1111/bjd.18086

Guercio BJ, Iyer G, Kidwai WZ, Lacouture ME, Ghafoor S, Rossi AM, et al. Treatment of metastatic extramammary Paget disease with combination ipilimumab and nivolumab: a case report. Case Rep Oncol 2021; 14: 430-438.

https://doi.org/10.1159/000514345 DOI: https://doi.org/10.1159/000514345

Published

2023-09-27

How to Cite

Fujimoto, M., Ishitsuka, Y., Tanemura, A., Nojima, S., & Fujimoto, M. (2023). Trousseau Syndrome in a Case of Extramammary Paget’s Disease. Acta Dermato-Venereologica, 103, adv9405. https://doi.org/10.2340/actadv.v103.9405

Issue

Section

Short Communication

Funding data