No demonstrable accumulation of 14C-vitamin D3 in developing rat teeth and bones

Authors

  • Sven Sjögren Department of Oral Pathology, Faculty of Odontology, University of Lund, Chapel Hill, N.C. 27514, USA
  • James Bawden Department of School of Dentistry, University of North Carolina, Chapel Hill, N.C., 27514, USA
  • Lars E. Hammarström Department of Oral Pathology, Karolinska Institute, Stockholm, Sweden
  • Åke Larsson Department of Oral Pathology, Faculty of Odontology, University of Lund, Chapel Hill, N.C. 27514, USA

DOI:

https://doi.org/10.3109/00016357809026367

Abstract

SjÖgren, S., Bawden, J., HammarstrÖm, L.E. & Larsson, Å. No demonstrable accumulation of 14C-vitamin D3 in developing rat teeth and bones. Acta Odont. Scand. 36, 51–55

The distribution of 14C-vitamin D3 administered subcutaneously in arachidic oil to 6-day-old suckling rats has been examined autoradiographically. The animals were sacrificed 1,2,4 and 8 days after injection. The autoradiographic exposure time was 4 months. The sectioning and exposure was performed in a freeze-room. Radioactivity was found mainly in the liver, kidney, intestines and fat depots. No uptake was found in developing teeth or bones.

 

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Published

1978-01-01

Issue

Vol. 36 No. 1 (1978): Acta Odontologica Scandinavica

Section

Articles