Characterization of Collagen Biosynthesis in Rabbit Dental Pulp In Vitro

Authors

  • Veli-Jukka Uitto Departments of Medical Chemistry and Pharmacology, University of Helsinki, Finland
  • Risto Antila Departments of Medical Chemistry and Pharmacology, University of Helsinki, Finland

DOI:

https://doi.org/10.3109/00016357109026338

Keywords:

Collagen biosynthesis, Dental pulp, Rabbits

Abstract

Collagen biosynthesis in the dental pulp was studied by measuring the rate of 14C-hydroxyproline formation in vitro and assaying the activity of protocollagen proline hydroxylase (PPH). The maximal formation of 14C-hydroxyproline from 14C-proline in an incubation medium occurred between the pH values 7.4 and 8.2. No significant differences in the rate of collagen biosynthesis could be demonstrated between the molar and incisor pulps. The methods of the present study seem to be useful for further investigation on collagen metabolism in the dental pulp.

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Published

1971-01-01

Issue

Vol. 29 No. 5 (1971): Acta Odontologica Scandinavica

Section

Articles