Focal Epithelial Hyperplasia in Sweden

Authors

  • Tony Axéll Departments of Oral Surgery and Oral Pathology, School of Dentistry, University of Lund, Malmö, Sweden; Department of Oral Pathology, School of Dentistry, Karolinska Institute, Stockholm, Sweden
  • Lars Hammarström Departments of Oral Surgery and Oral Pathology, School of Dentistry, University of Lund, Malmö, Sweden; Department of Oral Pathology, School of Dentistry, Karolinska Institute, Stockholm, Sweden
  • Åke Larsson Departments of Oral Surgery and Oral Pathology, School of Dentistry, University of Lund, Malmö, Sweden

DOI:

https://doi.org/10.3109/00016358109162281

Keywords:

Papova virus, epidemiology, electron microscopy

Abstract

Abstract

A prevalence of 0.11 % of focal epithelial hyperplasia (FEH) was found among 20, 333 adult Swedes. There was no sex difference, the lesion was most prevalent in age groups above 45 years and the lesion was most frequent on the tongue. The frequency of FEH in 15, 132 consecutive routine biopsies was 0.26 %. Four FEH-cells were ultracstruturally examined. They exhibited a clear cytoplasm with scattered ribosomes, a peripheral condensation of tonofilaments, a central aggregation of chromatin clumps with loss of nuclear membrane and an accumulation of desmosome fragments. No viral particles could be identified in these FEH-cells.

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Published

1981-01-01