Effect of Xylitol in an Enzyme-Containing Dentifrice without Sodium Lauryl Sulfate on Mutans Streptococci in Vivo

Abstract

Janneson L, Renwrt S, Birklied D. Erect of xylitol in an enzyme-containing dentrifrice without sodium lauryl sulfate on mutans streptococci in vivo.

The aim of this investigation was to compare the effect of an enzyme-containing dentifrice with sodium lauyl sulfate bur with addition of xylitol (Zendium Dentine) on mutans streptococci (MS) in saliva and dental plaque with that of the same dentifrice without xylitol. The subjects were divided into a test group, using a dentifrice with 10% xylitol (part A) or 5% xylitol (part B), and a control group, using a dentifrice without xylitol, for 3 months. In part A the MS counts in saliva and plaque were significantly lower in the xylitol group (n=50) than in the control group (n=57) (P < 0.01 and P < 0.001, respectively). In part B (n=89 + 91), evaluating AIS counts in saliva only, no significant difference was found. Thus, this study demonstrated 1) that addition of 10% xylitol to an enzymie-containing dentifrice without sodium lauryl sulfate has an inhibitory effect on MS counts in saliva and dental plaque, and 2) that the inhibitory effect seems to be dose-dependent.