Onset and progression of dental erosion in a mouse model
DOI:
https://doi.org/10.2340/aos.v83.41193Keywords:
Acidic drinks, Dental enamel, Mouse model, Scanning electron microscopy, Tooth attrition, Tooth erosionAbstract
Objective: Purpose of this research was to examine the onset, progression and wear rates of dental erosion in an established mouse model.
Material and methods: Dental erosion in mice was experimentally induced, and the acidic effects of cola drink on their teeth after 2, 4 and 6-weeks were closely analysed by scanning electron microscopy. The tooth height and enamel or dentin loss were established.
Results: The dental erosion on the molars showed clear progression from 2 to 6 weeks. By the 2-week mark, a significant portion of enamel was already eroded, revealing the dentin on the lingual cusps. When adjusted for attritional wear, molars exposed to cola for 2 weeks showed a 35% drop in lingual tooth height compared to controls (533 μm vs. 818 μm). At 4 and 6 weeks, the cola-exposed group continued to display decreased lingual tooth heights by 40% (476 μm vs. 799 μm) and 43% (440 μm vs. 767 μm), respectively.
Conclusion: This study revealed significant acidic effects of cola drink on mouse molars as early as 2 weeks. These findings highlight the challenge of monitoring dental erosion clinically and underscore the importance of early preventive and intervention measures.
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Copyright (c) 2024 Julie Marie Haabeth Brox, Amela Tulek, Amer Sehic, Aida Mulic, Tor Paaske Utheim, Qalbi Khan
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Acta Odontologica Scandinavica publishes original research papers as well as critical reviews relevant to the diagnosis, epidemiology, health service, prevention, aetiology, pathogenesis, pathology, physiology, microbiology, development and treatment of diseases affecting tissues of the oral cavity and associated structures including papers on cause and effect or explanatory/associative relationships for experimental or observational studies.
