Low-frequency repetitive transcranial magnetic stimulation for patients with aphasia after stoke: A meta-analysis.
DOI:
https://doi.org/10.2340/16501977-1988Keywords:
transcranial magnetic stimulation, stroke, aphasia, meta-analysis.Abstract
OBJECTIVE: To perform a meta-analysis of studies investigating the effects of low-frequency repetitive transcranial magnetic stimulation on post-stroke aphasia. DATA SOURCES: Studies were identified by performing a search of electronic databases (MEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Knowledge) for articles published until June 2014. STUDY SELECTION: Randomized controlled trials (RCTs) reporting treatments with low-frequency repetitive transcranial magnetic stimulation in patients with post-stroke aphasia were included. The outcomes included naming, repetition, comprehension, changes in brain excitability, and adverse events. DATA EXTRACTION: Two independent reviewers extracted the data. Study quality was evaluated with the PEDro scale. DATA ANALYSIS: Of the 879 articles identified, 4 RCTs were included in the final analysis. Data synthesis showed that low-frequency repetitive transcranial magnetic stimulation was beneficial for post-stroke patients in terms of naming (standard mean difference (SMD) 0.51Downloads
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