Statin Therapy and Vascular Inflammation Detected by Positron Emission Tomography/Computed Tomography in Patients with Psoriasis

Authors

  • Hannah Kaiser Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, DK-2900 Hellerup, Denmark
  • Amanda Kvist-Hansen
  • Martin Krakauer
  • Peter Michael Gørtz
  • Kristoffer Mads Aaris Henningsen
  • Xing Wang
  • Christine Becker
  • Lone Skov
  • Peter Riis Hansen

DOI:

https://doi.org/10.2340/00015555-3752

Keywords:

psoriasis, statins, vascular inflammation, 18F-FDG-PET/CT

Abstract

Abstract is missing (Short communication)

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References

Alexandroff AB, Pauriah M, Camp RD, Lang CC, Struthers AD, Armstrong DJ. More than skin deep: atherosclerosis as a systemic manifestation of psoriasis. Br J Dermatol 2009; 161: 1-7.

DOI: https://doi.org/10.1111/j.1365-2133.2009.09281.x

Hjuler KF, Gormsen LC, Vendelbo MH, Egeberg A, Nielsen J, Iversen L. Increased global arterial and subcutaneous adipose tissue inflammation in patients with moderate-to-severe psoriasis. Br J Dermatol 2017; 176: 732-740.

DOI: https://doi.org/10.1111/bjd.15149

Figueroa AL, Abdelbaky A, Truong QA, Corsini E, MacNabb MH, Lavender ZR, et al. Measurement of arterial activity on routine FDG PET/CT images improves prediction of risk of future CV events. JACC Cardiovasc Imaging 2013; 6: 1250-1259.

DOI: https://doi.org/10.1016/j.jcmg.2013.08.006

Naik HB, Natarajan B, Stansky E, Ahlman MA, Teague H, Salahuddin T, et al. Severity of psoriasis associates with aortic vascular inflammation detected by FDG PET/CT and neutrophil activation in a prospective observational study. Arterioscler Thromb Vasc Biol 2015; 35: 2667-2676.

DOI: https://doi.org/10.1161/ATVBAHA.115.306460

Tawakol A, Fayad ZA, Mogg R, Alon A, Klimas MT, Dansky H, et al. Intensification of statin therapy results in a rapid reduction in atherosclerotic inflammation: results of a multicenter fluorodeoxyglucose- positron emission tomography/computed tomography feasibility study. J Am Coll Cardiol 2013; 62: 909-917.

DOI: https://doi.org/10.1016/j.jacc.2013.04.066

Bucerius J, Hyafil F, Verberne HJ, Slart RHJA, Lindner O, Sciagra R, et al. Position paper of the cardiovascular committee of the european association of nuclear medicine (EANM) on PET imaging of atherosclerosis. Eur J Nucl Med Mol Imaging 2016; 43: 780-792.

DOI: https://doi.org/10.1007/s00259-015-3259-3

Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the american college of cardiology/american heart association task force on clinical practice guidelines. Circulation 2019; 139: E1082-1143.

DOI: https://doi.org/10.1161/CIR.0000000000000698

Ports WC, Fayyad R, DeMicco DA, Laskey R, Wolk R. Effectiveness of lipid-lowering statin therapy in patients with and without psoriasis. Clin Drug Investig 2017; 37: 775-785.

DOI: https://doi.org/10.1007/s40261-017-0533-0

S. Antonopoulos A, Margaritis M, Lee R, Channon K, Antoniades C. Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials. Curr Pharm Des 2012; 18: 1519-1530.

DOI: https://doi.org/10.2174/138161212799504803

Reddy AS, Uceda DE, Al Najafi M, Dey AK, Mehta NN. PET scan with fludeoxyglucose/computed tomography in low-grade vascular inflammation. PET Clinics 2020; 15: 207-213.

DOI: https://doi.org/10.1016/j.cpet.2019.11.009

Rudd JHF, Myers KS, Bansilal S, Machac J, Rafique A, Farkouh M, et al. 18Fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible. Implications for atherosclerosis therapy trials. J Am Coll Cardiol 2007; 50: 892-896.

DOI: https://doi.org/10.1016/j.jacc.2007.05.024

Published

2021-02-24

How to Cite

Kaiser, H., Kvist-Hansen, A., Krakauer, M., Gørtz, P. M., Henningsen, K. M. A., Wang, X., … Riis Hansen, P. (2021). Statin Therapy and Vascular Inflammation Detected by Positron Emission Tomography/Computed Tomography in Patients with Psoriasis. Acta Dermato-Venereologica, 101(2), adv00406. https://doi.org/10.2340/00015555-3752

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