Circulating anticoagulant and serological tests for syphilis

Authors

  • Y. Shoenfeld
  • E. Shaulian
  • M. Shaklai
  • J. Kruglack
  • E. Feuerman
  • J. Pinkhas

DOI:

https://doi.org/10.2340/0001555560365367

Abstract

Circulating anticoagulant (CA) and particularly lupus anticoagulant are commonly associated with biological false-positive tests for syphilis (BFP-STS) in patients with collagen diseases. CA was presently found in the sera of 8 out of 30 subjects with chronic BFP-STS without collagen or autoimmune diseases. It was not found in any of the 21 patients with various stages of syphilis. In 5 out of 21 elderly subjects (age greater than 70 years) in whom a positive BFP-STS was detected, there was no CA. It is concluded that the association between CA and BFP-STS is found only in patients with collagen and autoimmune diseases and in some of the younger chronic BFP-STS reactors. It is not detected in syphilitic patients or elderly subjects in whom a high incidence of BFP-STS can be found. The difference in the incidence of this association is probably due to the differing biologic behaviour of these autoantibodies.

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Published

1980-07-07

How to Cite

Shoenfeld, Y., Shaulian, E., Shaklai, M., Kruglack, J., Feuerman, E., & Pinkhas, J. (1980). Circulating anticoagulant and serological tests for syphilis. Acta Dermato-Venereologica, 60(4), 365–367. https://doi.org/10.2340/0001555560365367

Issue

Section

Articles