Interleukin-18 levels in the plasma of psoriatic patients correlate with the extent of skin lesions and the PASI score
DOI:
https://doi.org/10.1080/00015550310016508Abstract
Interleukin-18 is a cytokine with a possible role in the pathogenesis of psoriasis. We examined subpopulations of peripheral blood lymphocytes and their expression of activation markers and correlated this with plasma levels of IL-18 and clinical disease severity in patients with psoriasis. We included 12 patients with psoriasis who had a PASI score from 15 to 48 and compared them to controls. IL-18 plasma concentrations were determined with an enzyme-linked immunosorbent assay. We observed a significant correlation between the IL-18 levels and the area of skin affected with psoriasis and the PASI score. We also observed an increase in NK cells and memory helper CD45RO + /CD4+cells.Downloads
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Published
2003-08-21
How to Cite
Pietrzak, A., Lecewicz-Torun, B., Chodorowska, G., & Rolinski, J. (2003). Interleukin-18 levels in the plasma of psoriatic patients correlate with the extent of skin lesions and the PASI score. Acta Dermato-Venereologica, 83(4), 262–265. https://doi.org/10.1080/00015550310016508
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