Contact allergy to the isomers of diglycidyl ether of bisphenol F
DOI:
https://doi.org/10.1080/00015550310005870Abstract
Diglycidyl ether of bisphenol A (DGEBA) is the monomer and main allergen in the most common epoxy resin, DGEBA-R. Epoxy resin(s) based on bisphenol F (DGEBF-R) contains the 3 isomers of the diglycidyl ether of bisphenol F. Contact allergy to these isomers (p,p'-DGEBF, o,p'-DGEBF and o,o'-DGEBF) has not previously been described in humans. To investigate contact allergies to the DGEBF isomers in patients with contact allergy to DGEBF-R, 9 patients were patch-tested with dilution series of the isomers. All 9 were found to have contact allergy to p,p'-DGEBF and 7/9 to o,p'-DGEBF. Additionally, of 20 workers employed in epoxy-based manufacture and with contact allergy to DGEBA-R and DGEBF-R, 18 reacted to p,p'-DGEBF and 15/20 to o,p'-DGEBF. According to a guinea pig maximization test, all 3 DGEBF isomers are strong sensitizers. Still, o,o'-DGEBF elicited only 3 positive reactions in all participants.Downloads
Downloads
Published
How to Cite
Issue
Section
License
All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.