Repeated Open Application Tests (ROAT) in Patients Allergic to Colophony--Evaluated Visually and with Bioengineering Techniques.
DOI:
https://doi.org/10.1080/000155598433476Abstract
It is desirable to further evaluate the clinical relevance of a positive patch test. The repeated open application test (ROAT) has been suggested as such a supplementary method. To compare the results of patch testing with the outcome of ROATs;13 colophony-sensitive subjects and 9 controls were patch-tested with colophony in a serial dilution test. Five microliters;of three concentrations of a colophony solution and the vehicle were then applied to small test areas on the lower arm;once daily for 2 weeks. Prior to each application;all test sites were examined visually and with bioengineering techniques. In the ROATs;10/13 colophony-sensitive subjects--but no controls--reacted to a 20% colophonyDownloads
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