Malignant Eccrine Porocarcinoma in Finland During 2007 to 2017

Authors

  • Anna-Stiina Meriläinen
  • Eero Pukkala
  • Tom Böhling
  • Virve Koljonen Department of Plastic Surgery, University of Helsinki and Helsinki University Hospital, FIN-00290 Helsinki, Finland

DOI:

https://doi.org/10.2340/00015555-3718

Keywords:

eccrine porocarcinoma, incidence, survival

Abstract

Malignant eccrine porocarcinoma is a rare skin adnexal cancer arising from the sweat glands. Little is known about the epidemiology and incidence of eccrine porocarcinoma. This registry-based study examined the epidemiology and incidence data for eccrine porocarcinoma from the Finnish Cancer Registry. The study included all persons diagnosed with eccrine porocarcinoma in 2007 to 2017. There were 69 cases in the study period; 34 (49%) male and 35 (51%) female patients. Mean age at diagnosis was 75.5 years. Incidence for men was 0.06 per 100,000 person-years and for women 0.04 per 100,000 person-years adjusted for age according to the World Standard Population. Incidence increased with age. There was one eccrine porocarcinoma-specific death among the 69 patients. The incidence of eccrine porocarcinoma in Finland is therefore low. The mean age at time of diagnosis and the location of eccrine porocarcinoma are consistent with previous reports. The survival of patients with eccrine porocarcinoma is high.

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References

Shaw M, McKee PH, Lowe D, Black MM. Malignant eccrine poroma: a study of twenty-seven cases. Br J Dermatol 1982; 107: 675-680.

DOI: https://doi.org/10.1111/j.1365-2133.1982.tb00527.x

Robson A, Greene J, Ansari N, Kim B, Seed PT, McKee PH, et al. Eccrine porocarcinoma (malignant eccrine poroma): a clinicopathologic study of 69 cases. Am J Surg Pathol 2001; 25: 710-720.

DOI: https://doi.org/10.1097/00000478-200106000-00002

Belin E, Ezzedine K, Stanislas S, Lalanne N, Beylot-Barry M, Taieb A, et al. Factors in the surgical management of primary eccrine porocarcinoma: prognostic histological factors can guide the surgical procedure. Br J Dermatol 2011; 165: 985-989.

DOI: https://doi.org/10.1111/j.1365-2133.2011.10486.x

Nazemi A, Higgins S, Swift R, In G, Miller K, Wysong A. Eccrine porocarcinoma: new insights and a systematic review of the literature. Dermatol Surg 2018; 44: 1247-1261.

DOI: https://doi.org/10.1097/DSS.0000000000001566

Riera-Leal L, Guevara-Gutierrez E, Barrientos-Garcia JG, Madrigal-Kasem R, Briseno-Rodriguez G, Tlacuilo-Parra A. Eccrine porocarcinoma: epidemiologic and histopathologic characteristics. Int J Dermatol 2015; 54: 580-586.

DOI: https://doi.org/10.1111/ijd.12714

Stam H, Lohuis PJ, Zupan-Kajcovski B, Wouters MW, van der Hage JA, Visser O. Increasing incidence and survival of a rare skin cancer in the Netherlands. A population-based study of 2,220 cases of skin adnexal carcinoma. J Surg Oncol 2013; 107: 822-827.

DOI: https://doi.org/10.1002/jso.23331

Pinkus H, Mehregan AH. Epidermotropic eccrine carcinoma. A case combining features of eccrine poroma and Paget's dermatosis. Arch Dermatol 1963; 88: 597-606.

DOI: https://doi.org/10.1001/archderm.1963.01590230105015

Mishima Y, Morioka S. Oncogenic differentiation of the intraepidermal eccrine sweat duct: eccrine poroma, poroepithelioma and porocarcinoma. Dermatologica 1969; 138: 238-250.

DOI: https://doi.org/10.1159/000253989

Salih AM, Kakamad FH, Essa RA, Rauf GM, S AM, H MS, et al. Porocarcinoma: a systematic review of literature with a single case report. Int J Surg Case Rep 2017; 30: 13-16.

DOI: https://doi.org/10.1016/j.ijscr.2016.10.051

Behbahani S, Malerba S, Karanfilian KM, Warren CJ, Alhatem A, Samie FH. Demographics and outcomes of eccrine porocarcinoma: results from the National Cancer Database. Br J Dermatol 2020; 183: 161-163.

DOI: https://doi.org/10.1111/bjd.18874

Sawaya JL, Khachemoune A. Poroma: a review of eccrine, apocrine, and malignant forms. Int J Dermatol 2014; 53: 1053-1061.

DOI: https://doi.org/10.1111/ijd.12448

Pukkala E, Engholm G, Hojsgaard Schmidt LK, Storm H, Khan S, Lambe M, et al. Nordic Cancer Registries - an overview of their procedures and data comparability. Acta Oncol 2018; 57: 440-455.

DOI: https://doi.org/10.1080/0284186X.2017.1407039

Segi M, Fujisaku S. Cancer mortality for selected sites in 24 countries (1950-1957): Department of Public Health, Tohoku University School of Medicine; 1960.

Pace M, Lanzieri G, Glickman M, Zupani? T. Revision of the European Standard Population: report of Eurostat's task force: Publications Office of the European Union; 2013.

Goon PKC, Gurung P, Levell NJ, Subramanian P, Yong ASW, Lee KYC, et al. Eccrine porocarcinoma of the skin is rising in incidence in the East of England. Acta Derm Venereol 2018; 98: 991-992.

DOI: https://doi.org/10.2340/00015555-3000

Mehregan AH, Hashimoto K, Rahbari H. Eccrine adenocarcinoma. A clinicopathologic study of 35 cases. Arch Dermatol 1983; 119: 104-114.

DOI: https://doi.org/10.1001/archderm.1983.01650260012008

Tolkachjov SN, Schmitt AR, Muzic JG, Weaver AL, Baum CL. Incidence and clinical features of rare cutaneous malignancies in Olmsted County, Minnesota, 2000 to 2010. Dermatol Surg 2017; 43: 116-124.

DOI: https://doi.org/10.1097/DSS.0000000000000936

Avraham JB, Villines D, Maker VK, August C, Maker AV. Survival after resection of cutaneous adnexal carcinomas with eccrine differentiation: risk factors and trends in outcomes. J Surg Oncol 2013; 108: 57-62.

DOI: https://doi.org/10.1002/jso.23346

Sahi H, Their J, Gissler M, Koljonen V. Merkel cell carcinoma treatment in Finland in 1986-2016 - a real-world data study. Cancers (Basel) 2020; 12: 1224.

DOI: https://doi.org/10.3390/cancers12051224

Goto K, Takai T, Fukumoto T, Anan T, Kimura T, Ansai S, et al. CD117 (KIT) is a useful immunohistochemical marker for differentiating porocarcinoma from squamous cell carcinoma. J Cutan Pathol 2016; 43: 219-226.

DOI: https://doi.org/10.1111/cup.12632

Kurisu Y, Tsuji M, Yasuda E, Shibayama Y. A case of eccrine porocarcinoma: usefulness of immunostain for s-100 protein in the diagnoses of recurrent and metastatic dedifferentiated lesions. Ann Dermatol 2013; 25: 348-351.

DOI: https://doi.org/10.5021/ad.2013.25.3.348

Nakazawa T, Kondo T, Sato E, Motosugi U, Niu D, Mochizuki K, et al. Subcutaneous porocarcinoma clinically presenting as a soft tissue tumor. J Cutan Pathol 2015; 42: 897-902.

DOI: https://doi.org/10.1111/cup.12576

Published

2021-01-05

How to Cite

Meriläinen, A.-S., Pukkala, E., Böhling, T., & Koljonen, V. (2021). Malignant Eccrine Porocarcinoma in Finland During 2007 to 2017. Acta Dermato-Venereologica, 101(1), adv00363. https://doi.org/10.2340/00015555-3718